FATS regulates polyamine biosynthesis by promoting ODC degradation in an ERβ-dependent manner in non-small-cell lung cancer

Polyamine biosynthesis is an essential metabolic pathway for cell growth and differentiation in non-small-cell lung cancer (NSCLC). Fragile-site associated tumour suppressor (FATS) is a novel gene involved in cancer. The results of our previous study showed that FATS-mediated polyubiquitination of p...

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Veröffentlicht in:	Cell death & disease 2020-10, Vol.11 (10), p.839, Article 839
Hauptverfasser:	Qiu, Li, Hu, Linfei, Wang, Huijuan, Li, Jinling, Ruan, Xianhui, Sun, Bingsheng, Zhi, Jingtai, Zheng, Xiangqian, Gu, Lin, Gao, Ming, Kong, Pengzhou, Zhang, Jun
Format:	Artikel
Sprache:	eng
Schlagworte:	14/35 38/109 38/77 38/89 38/90 59/5 631/80/39/2346 631/80/82/23 64/60 82/51 96/2 Antibodies Biochemistry Biomedical and Life Sciences Carcinoma, Non-Small-Cell Lung - genetics Carcinoma, Non-Small-Cell Lung - metabolism Cell Biology Cell Culture Cell Cycle - genetics Cell Proliferation - genetics Estrogen Receptor beta - genetics Genes, Tumor Suppressor - physiology Humans Immunology Life Sciences Lung Neoplasms - genetics RNA, Messenger - metabolism
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