Exosomes secreted under hypoxia enhance stemness in Ewing’s sarcoma through miR-210 delivery

Intercellular communication between tumor cells within the hypoxic microenvironment promote aggressiveness and poor patient prognoses for reasons that remain unclear. Here we show that hypoxic Ewing’s sarcoma (EWS) cells release exosomes that promote sphere formation, a stem-like phenotype, in EWS c...

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Veröffentlicht in:	Oncotarget 2020-10, Vol.11 (40), p.3633-3645
Hauptverfasser:	Kling, Matthew J., Chaturvedi, Nagendra K., Kesherwani, Varun, Coulter, Don W., McGuire, Timothy R., Sharp, J. Graham, Joshi, Shantaram S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Research Paper
Online-Zugang:	Volltext
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