Coronary angiography or not after cardiac arrest without ST segment elevation: A systematic review and meta-analysis
This meta-analysis aimed to review the available evidence and evaluate the necessity of immediate coronary angiography (CAG) to obtain positive outcomes for out-of-hospital cardiac arrest (OHCA) patients without ST segment elevation. Web of Science, PubMed, Embase, Chinese National Knowledge Infrast...
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| Veröffentlicht in: | Medicine (Baltimore) 2020-10, Vol.99 (41), p.e22197-e22197 |
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| container_title | Medicine (Baltimore) |
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| creator | Yang, Meng-Chang Meng-Jun, Wu Xiao-Yan, Xu Peng, Kevin L. Peng, Yong G. Wang, Ru-Rong |
| description | This meta-analysis aimed to review the available evidence and evaluate the necessity of immediate coronary angiography (CAG) to obtain positive outcomes for out-of-hospital cardiac arrest (OHCA) patients without ST segment elevation.
Web of Science, PubMed, Embase, Chinese National Knowledge Infrastructure, Wanfang, and SinoMed databases.
We included observational and case-control studies of outcomes among individuals without ST segment elevation experiencing OHCA who had immediate, delayed, or no CAG.
We extracted study details, as well as patient characteristics and outcomes.
Six studies (n = 2665) investigating mortality until discharge demonstrated a significant increase in survival benefit with early CAG (odds ratio [OR] = 1.78; 95%CI = 1.51-2.11; I = 81%; P |
| doi_str_mv | 10.1097/MD.0000000000022197 |
| format | Article |
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Web of Science, PubMed, Embase, Chinese National Knowledge Infrastructure, Wanfang, and SinoMed databases.
We included observational and case-control studies of outcomes among individuals without ST segment elevation experiencing OHCA who had immediate, delayed, or no CAG.
We extracted study details, as well as patient characteristics and outcomes.
Six studies (n = 2665) investigating mortality until discharge demonstrated a significant increase in survival benefit with early CAG (odds ratio [OR] = 1.78; 95%CI = 1.51-2.11; I = 81%; P < .0001). Seven studies (n = 2909) showed a significant preservation of neurological functions with early CAG at discharge (OR = 1.66; 95%CI = 1.37-2.02; P < .00001). Four studies (n = 1357) investigating survival outcomes with middle-term follow-up revealed no significant benefit with early CAG (OR = 1.21; 95%CI = 0.93-1.57; I = 66%; P = .15).
Our meta-analysis demonstrates that there may be significant benefits in performing immediate CAG on patients who experience OHCA without ST segment elevation.</description><identifier>ISSN: 0025-7974</identifier><identifier>EISSN: 1536-5964</identifier><identifier>DOI: 10.1097/MD.0000000000022197</identifier><identifier>PMID: 33031262</identifier><language>eng</language><publisher>United States: Lippincott Williams & Wilkins</publisher><subject>Coronary Angiography ; Humans ; Out-of-Hospital Cardiac Arrest - diagnostic imaging ; Out-of-Hospital Cardiac Arrest - mortality ; Survival Rate ; Systematic Review and Meta-Analysis ; Time Factors</subject><ispartof>Medicine (Baltimore), 2020-10, Vol.99 (41), p.e22197-e22197</ispartof><rights>Lippincott Williams & Wilkins</rights><rights>Copyright © 2020 the Author(s). Published by Wolters Kluwer Health, Inc. 2020</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c3559-f227d005bbf46024aa250cc6b3eed46b38b48e4c2d02f019e27be779b26f17693</cites><orcidid>0000-0002-1247-1665</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7544299/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7544299/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,860,881,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/33031262$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Yang, Meng-Chang</creatorcontrib><creatorcontrib>Meng-Jun, Wu</creatorcontrib><creatorcontrib>Xiao-Yan, Xu</creatorcontrib><creatorcontrib>Peng, Kevin L.</creatorcontrib><creatorcontrib>Peng, Yong G.</creatorcontrib><creatorcontrib>Wang, Ru-Rong</creatorcontrib><title>Coronary angiography or not after cardiac arrest without ST segment elevation: A systematic review and meta-analysis</title><title>Medicine (Baltimore)</title><addtitle>Medicine (Baltimore)</addtitle><description>This meta-analysis aimed to review the available evidence and evaluate the necessity of immediate coronary angiography (CAG) to obtain positive outcomes for out-of-hospital cardiac arrest (OHCA) patients without ST segment elevation.
Web of Science, PubMed, Embase, Chinese National Knowledge Infrastructure, Wanfang, and SinoMed databases.
We included observational and case-control studies of outcomes among individuals without ST segment elevation experiencing OHCA who had immediate, delayed, or no CAG.
We extracted study details, as well as patient characteristics and outcomes.
Six studies (n = 2665) investigating mortality until discharge demonstrated a significant increase in survival benefit with early CAG (odds ratio [OR] = 1.78; 95%CI = 1.51-2.11; I = 81%; P < .0001). Seven studies (n = 2909) showed a significant preservation of neurological functions with early CAG at discharge (OR = 1.66; 95%CI = 1.37-2.02; P < .00001). Four studies (n = 1357) investigating survival outcomes with middle-term follow-up revealed no significant benefit with early CAG (OR = 1.21; 95%CI = 0.93-1.57; I = 66%; P = .15).
Our meta-analysis demonstrates that there may be significant benefits in performing immediate CAG on patients who experience OHCA without ST segment elevation.</description><subject>Coronary Angiography</subject><subject>Humans</subject><subject>Out-of-Hospital Cardiac Arrest - diagnostic imaging</subject><subject>Out-of-Hospital Cardiac Arrest - mortality</subject><subject>Survival Rate</subject><subject>Systematic Review and Meta-Analysis</subject><subject>Time Factors</subject><issn>0025-7974</issn><issn>1536-5964</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpdkU1vEzEQhi0EoqHwC5CQj1y2-HMdc0CqkvIhteJAOVte72zWsLtObW-i_HscUgplLqMZv_N4Ri9Crym5oESrdzfrC_I3GKNaPUELKnldSV2Lp2hRurJSWokz9CKlH4RQrph4js44J5yymi1QXoUYJhsP2E4bHzbRbvsDDhFPIWPbZYjY2dh667CNEVLGe5_7MGf87RYn2IwwZQwD7Gz2YXqPL3E6pAxjKR2OsPOwL-QWj5BtZSc7HJJPL9Gzzg4JXt3nc_T949Xt6nN1_fXTl9XldeW4lLrqGFMtIbJpOlETJqxlkjhXNxygFSUtG7EE4VhLWEeoBqYaUEo3rO6oqjU_Rx9O3O3cjNC6smu0g9lGP5aLTbDePH6ZfG82YWeUFILpI-DtPSCGu7lcb0afHAyDnSDMyTAhtJZyqVWR8pPUxZBShO7hG0rM0S9zszb_-1Wm3vy74cPMH4OKQJwE-zAUM9LPYd5DND3YIfe_eVJpVjHCCCVEk-rY0vwXAS2ivw</recordid><startdate>20201009</startdate><enddate>20201009</enddate><creator>Yang, Meng-Chang</creator><creator>Meng-Jun, Wu</creator><creator>Xiao-Yan, Xu</creator><creator>Peng, Kevin L.</creator><creator>Peng, Yong G.</creator><creator>Wang, Ru-Rong</creator><general>Lippincott Williams & Wilkins</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0002-1247-1665</orcidid></search><sort><creationdate>20201009</creationdate><title>Coronary angiography or not after cardiac arrest without ST segment elevation: A systematic review and meta-analysis</title><author>Yang, Meng-Chang ; Meng-Jun, Wu ; Xiao-Yan, Xu ; Peng, Kevin L. ; Peng, Yong G. ; Wang, Ru-Rong</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3559-f227d005bbf46024aa250cc6b3eed46b38b48e4c2d02f019e27be779b26f17693</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Coronary Angiography</topic><topic>Humans</topic><topic>Out-of-Hospital Cardiac Arrest - diagnostic imaging</topic><topic>Out-of-Hospital Cardiac Arrest - mortality</topic><topic>Survival Rate</topic><topic>Systematic Review and Meta-Analysis</topic><topic>Time Factors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Yang, Meng-Chang</creatorcontrib><creatorcontrib>Meng-Jun, Wu</creatorcontrib><creatorcontrib>Xiao-Yan, Xu</creatorcontrib><creatorcontrib>Peng, Kevin L.</creatorcontrib><creatorcontrib>Peng, Yong G.</creatorcontrib><creatorcontrib>Wang, Ru-Rong</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Medicine (Baltimore)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Yang, Meng-Chang</au><au>Meng-Jun, Wu</au><au>Xiao-Yan, Xu</au><au>Peng, Kevin L.</au><au>Peng, Yong G.</au><au>Wang, Ru-Rong</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Coronary angiography or not after cardiac arrest without ST segment elevation: A systematic review and meta-analysis</atitle><jtitle>Medicine (Baltimore)</jtitle><addtitle>Medicine (Baltimore)</addtitle><date>2020-10-09</date><risdate>2020</risdate><volume>99</volume><issue>41</issue><spage>e22197</spage><epage>e22197</epage><pages>e22197-e22197</pages><issn>0025-7974</issn><eissn>1536-5964</eissn><abstract>This meta-analysis aimed to review the available evidence and evaluate the necessity of immediate coronary angiography (CAG) to obtain positive outcomes for out-of-hospital cardiac arrest (OHCA) patients without ST segment elevation.
Web of Science, PubMed, Embase, Chinese National Knowledge Infrastructure, Wanfang, and SinoMed databases.
We included observational and case-control studies of outcomes among individuals without ST segment elevation experiencing OHCA who had immediate, delayed, or no CAG.
We extracted study details, as well as patient characteristics and outcomes.
Six studies (n = 2665) investigating mortality until discharge demonstrated a significant increase in survival benefit with early CAG (odds ratio [OR] = 1.78; 95%CI = 1.51-2.11; I = 81%; P < .0001). Seven studies (n = 2909) showed a significant preservation of neurological functions with early CAG at discharge (OR = 1.66; 95%CI = 1.37-2.02; P < .00001). Four studies (n = 1357) investigating survival outcomes with middle-term follow-up revealed no significant benefit with early CAG (OR = 1.21; 95%CI = 0.93-1.57; I = 66%; P = .15).
Our meta-analysis demonstrates that there may be significant benefits in performing immediate CAG on patients who experience OHCA without ST segment elevation.</abstract><cop>United States</cop><pub>Lippincott Williams & Wilkins</pub><pmid>33031262</pmid><doi>10.1097/MD.0000000000022197</doi><orcidid>https://orcid.org/0000-0002-1247-1665</orcidid><oa>free_for_read</oa></addata></record> |
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| source | Wolters Kluwer Open Health; MEDLINE; DOAJ Directory of Open Access Journals; IngentaConnect Free/Open Access Journals; EZB-FREE-00999 freely available EZB journals; PubMed Central; Alma/SFX Local Collection |
| subjects | Coronary Angiography Humans Out-of-Hospital Cardiac Arrest - diagnostic imaging Out-of-Hospital Cardiac Arrest - mortality Survival Rate Systematic Review and Meta-Analysis Time Factors |
| title | Coronary angiography or not after cardiac arrest without ST segment elevation: A systematic review and meta-analysis |
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