DNA targeting by subtype I-D CRISPR–Cas shows type I and type III features

Prokaryotic CRISPR–Cas immune systems are classified into six types based on their effector complexes which cleave dsDNA specifically (types I, II and V), ssRNA exclusively (type VI) or both ssRNA via a ruler mechanism and ssDNA unspecifically (type III). To date, no specific cleavage of ssDNA targe...

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Veröffentlicht in:	Nucleic acids research 2020-10, Vol.48 (18), p.10470-10478
Hauptverfasser:	Lin, Jinzhong, Fuglsang, Anders, Kjeldsen, Anders Lynge, Sun, Kaiyan, Bhoobalan-Chitty, Yuvaraj, Peng, Xu
Format:	Artikel
Sprache:	eng
Schlagworte:	Life Sciences RNA and RNA-protein complexes
Online-Zugang:	Volltext
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