Case Report: Coronavirus Disease and Pulmonary Tuberculosis in Patients with Human Immunodeficiency Virus: Report of Two Cases
Coinfection of SARS-CoV-2/ (MTB) in patients with HIV/AIDS has not been previously reported. Here, we present two cases of coinfection of SARS-CoV-2 and MTB in patients with HIV. The first case is a 39-year-old patient who was admitted with a 7-day history of fever, myalgia, headache, and cough. The...
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creator | Gadelha Farias, Luís Arthur Brasil Gomes Moreira, Ana Livia Austregésilo Corrêa, Eduardo Landim de Oliveira Lima, Cicero Allan Lopes, Isadora Maria Praciano de Holanda, Pablo Eliack Linhares Nunes, Fernanda Remígio Pires Neto, Roberto da Justa |
description | Coinfection of SARS-CoV-2/
(MTB) in patients with HIV/AIDS has not been previously reported. Here, we present two cases of coinfection of SARS-CoV-2 and MTB in patients with HIV. The first case is a 39-year-old patient who was admitted with a 7-day history of fever, myalgia, headache, and cough. The second patient is a 43-year-old man who had a 1-month history of cough with hemoptoic sputum, evolving to mild respiratory distress in the last 7 days. Both patients already had pulmonary tuberculosis and subsequently developed SARS-CoV-2 infection during the 2020 pandemic. Nonadherence to antiretroviral treatment may have been a factor in the clinical worsening of the patients. |
doi_str_mv | 10.4269/ajtmh.20-0737 |
format | Article |
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(MTB) in patients with HIV/AIDS has not been previously reported. Here, we present two cases of coinfection of SARS-CoV-2 and MTB in patients with HIV. The first case is a 39-year-old patient who was admitted with a 7-day history of fever, myalgia, headache, and cough. The second patient is a 43-year-old man who had a 1-month history of cough with hemoptoic sputum, evolving to mild respiratory distress in the last 7 days. Both patients already had pulmonary tuberculosis and subsequently developed SARS-CoV-2 infection during the 2020 pandemic. Nonadherence to antiretroviral treatment may have been a factor in the clinical worsening of the patients.</description><identifier>ISSN: 0002-9637</identifier><identifier>EISSN: 1476-1645</identifier><identifier>DOI: 10.4269/ajtmh.20-0737</identifier><identifier>PMID: 32815515</identifier><language>eng</language><publisher>United States: Institute of Tropical Medicine</publisher><subject>Acquired immune deficiency syndrome ; Adult ; AIDS ; Anti-HIV Agents - therapeutic use ; Betacoronavirus - pathogenicity ; Case reports ; Coinfection ; Coronavirus Infections - drug therapy ; Coronavirus Infections - immunology ; Coronavirus Infections - microbiology ; Coronavirus Infections - virology ; Cough - drug therapy ; Cough - immunology ; Cough - microbiology ; Cough - virology ; COVID-19 ; HIV ; HIV - pathogenicity ; HIV Infections - drug therapy ; HIV Infections - immunology ; HIV Infections - microbiology ; HIV Infections - virology ; Human immunodeficiency virus ; Humans ; Male ; Mycobacterium tuberculosis - pathogenicity ; Pandemics ; Patient Compliance - psychology ; Patients ; Pneumonia, Viral - drug therapy ; Pneumonia, Viral - immunology ; Pneumonia, Viral - microbiology ; Pneumonia, Viral - virology ; Respiratory Distress Syndrome - drug therapy ; Respiratory Distress Syndrome - immunology ; Respiratory Distress Syndrome - microbiology ; Respiratory Distress Syndrome - virology ; SARS-CoV-2 ; Severe acute respiratory syndrome coronavirus 2 ; Tomography, X-Ray Computed ; Tuberculosis ; Tuberculosis, Pulmonary - drug therapy ; Tuberculosis, Pulmonary - immunology ; Tuberculosis, Pulmonary - microbiology ; Tuberculosis, Pulmonary - virology</subject><ispartof>The American journal of tropical medicine and hygiene, 2020-10, Vol.103 (4), p.1593-1596</ispartof><rights>Copyright Institute of Tropical Medicine Oct 2020</rights><rights>The American Society of Tropical Medicine and Hygiene 2020</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c415t-92e256143e7c26ec09082f8f36bd38ebe606d784232a62989e3ea8d98fedb65e3</citedby><cites>FETCH-LOGICAL-c415t-92e256143e7c26ec09082f8f36bd38ebe606d784232a62989e3ea8d98fedb65e3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7543835/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7543835/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/32815515$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Gadelha Farias, Luís Arthur Brasil</creatorcontrib><creatorcontrib>Gomes Moreira, Ana Livia</creatorcontrib><creatorcontrib>Austregésilo Corrêa, Eduardo</creatorcontrib><creatorcontrib>Landim de Oliveira Lima, Cicero Allan</creatorcontrib><creatorcontrib>Lopes, Isadora Maria Praciano</creatorcontrib><creatorcontrib>de Holanda, Pablo Eliack Linhares</creatorcontrib><creatorcontrib>Nunes, Fernanda Remígio</creatorcontrib><creatorcontrib>Pires Neto, Roberto da Justa</creatorcontrib><title>Case Report: Coronavirus Disease and Pulmonary Tuberculosis in Patients with Human Immunodeficiency Virus: Report of Two Cases</title><title>The American journal of tropical medicine and hygiene</title><addtitle>Am J Trop Med Hyg</addtitle><description>Coinfection of SARS-CoV-2/
(MTB) in patients with HIV/AIDS has not been previously reported. Here, we present two cases of coinfection of SARS-CoV-2 and MTB in patients with HIV. The first case is a 39-year-old patient who was admitted with a 7-day history of fever, myalgia, headache, and cough. The second patient is a 43-year-old man who had a 1-month history of cough with hemoptoic sputum, evolving to mild respiratory distress in the last 7 days. Both patients already had pulmonary tuberculosis and subsequently developed SARS-CoV-2 infection during the 2020 pandemic. Nonadherence to antiretroviral treatment may have been a factor in the clinical worsening of the patients.</description><subject>Acquired immune deficiency syndrome</subject><subject>Adult</subject><subject>AIDS</subject><subject>Anti-HIV Agents - therapeutic use</subject><subject>Betacoronavirus - pathogenicity</subject><subject>Case reports</subject><subject>Coinfection</subject><subject>Coronavirus Infections - drug therapy</subject><subject>Coronavirus Infections - immunology</subject><subject>Coronavirus Infections - microbiology</subject><subject>Coronavirus Infections - virology</subject><subject>Cough - drug therapy</subject><subject>Cough - immunology</subject><subject>Cough - microbiology</subject><subject>Cough - virology</subject><subject>COVID-19</subject><subject>HIV</subject><subject>HIV - pathogenicity</subject><subject>HIV Infections - drug therapy</subject><subject>HIV Infections - immunology</subject><subject>HIV Infections - microbiology</subject><subject>HIV Infections - virology</subject><subject>Human immunodeficiency virus</subject><subject>Humans</subject><subject>Male</subject><subject>Mycobacterium tuberculosis - pathogenicity</subject><subject>Pandemics</subject><subject>Patient Compliance - psychology</subject><subject>Patients</subject><subject>Pneumonia, Viral - drug therapy</subject><subject>Pneumonia, Viral - immunology</subject><subject>Pneumonia, Viral - microbiology</subject><subject>Pneumonia, Viral - virology</subject><subject>Respiratory Distress Syndrome - drug therapy</subject><subject>Respiratory Distress Syndrome - immunology</subject><subject>Respiratory Distress Syndrome - microbiology</subject><subject>Respiratory Distress Syndrome - virology</subject><subject>SARS-CoV-2</subject><subject>Severe acute respiratory syndrome coronavirus 2</subject><subject>Tomography, X-Ray Computed</subject><subject>Tuberculosis</subject><subject>Tuberculosis, Pulmonary - drug therapy</subject><subject>Tuberculosis, Pulmonary - immunology</subject><subject>Tuberculosis, Pulmonary - microbiology</subject><subject>Tuberculosis, Pulmonary - virology</subject><issn>0002-9637</issn><issn>1476-1645</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpdkc1v1DAUxC0EokvhyBVZ4sIlxR_xR3pAQgu0lSpRoYWr5TgvrFdJvNhxq17423HabQWc3mF-mnmjQeg1JSc1k817u5vH7QkjFVFcPUErWitZUVmLp2hFCGFVI7k6Qi9S2hFCNaP0OTriTFMhqFih32ubAH-DfYjzKV6HGCZ77WNO-JNPsGh26vBVHsYixFu8yS1El4eQfMJ-wld29jDNCd_4eYvP82gnfDGOeQod9N4Vzd3iH4vh6SEFhx5vbgJegtNL9Ky3Q4JXh3uMvn_5vFmfV5dfzy7WHy8rV1MxVw0DJiStOSjHJDjSEM163XPZdlxDC5LITumacWYla3QDHKzuGt1D10oB_Bh9uPfd53aEzpWXox3MPvqxtDLBevOvMvmt-RmujRI111wUg3cHgxh-ZUizGX1yMAx2gpCTYTUXSkhxh779D92FHKdSr1BCK1UzzQtV3VMuhpQi9I_PUGKWZc3dsoYRsyxb-Dd_N3ikH6bkfwD7DaIC</recordid><startdate>20201001</startdate><enddate>20201001</enddate><creator>Gadelha Farias, Luís Arthur Brasil</creator><creator>Gomes Moreira, Ana Livia</creator><creator>Austregésilo Corrêa, Eduardo</creator><creator>Landim de Oliveira Lima, Cicero Allan</creator><creator>Lopes, Isadora Maria Praciano</creator><creator>de Holanda, Pablo Eliack Linhares</creator><creator>Nunes, Fernanda Remígio</creator><creator>Pires Neto, Roberto da Justa</creator><general>Institute of Tropical Medicine</general><general>The American Society of Tropical Medicine and Hygiene</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20201001</creationdate><title>Case Report: Coronavirus Disease and Pulmonary Tuberculosis in Patients with Human Immunodeficiency Virus: Report of Two Cases</title><author>Gadelha Farias, Luís Arthur Brasil ; 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subjects | Acquired immune deficiency syndrome Adult AIDS Anti-HIV Agents - therapeutic use Betacoronavirus - pathogenicity Case reports Coinfection Coronavirus Infections - drug therapy Coronavirus Infections - immunology Coronavirus Infections - microbiology Coronavirus Infections - virology Cough - drug therapy Cough - immunology Cough - microbiology Cough - virology COVID-19 HIV HIV - pathogenicity HIV Infections - drug therapy HIV Infections - immunology HIV Infections - microbiology HIV Infections - virology Human immunodeficiency virus Humans Male Mycobacterium tuberculosis - pathogenicity Pandemics Patient Compliance - psychology Patients Pneumonia, Viral - drug therapy Pneumonia, Viral - immunology Pneumonia, Viral - microbiology Pneumonia, Viral - virology Respiratory Distress Syndrome - drug therapy Respiratory Distress Syndrome - immunology Respiratory Distress Syndrome - microbiology Respiratory Distress Syndrome - virology SARS-CoV-2 Severe acute respiratory syndrome coronavirus 2 Tomography, X-Ray Computed Tuberculosis Tuberculosis, Pulmonary - drug therapy Tuberculosis, Pulmonary - immunology Tuberculosis, Pulmonary - microbiology Tuberculosis, Pulmonary - virology |
title | Case Report: Coronavirus Disease and Pulmonary Tuberculosis in Patients with Human Immunodeficiency Virus: Report of Two Cases |
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