Rosmarinic acid-induced apoptosis and cell cycle arrest in triple-negative breast cancer cells

Rosmarinic acid (RA) is a polyphenolic compound with various pharmacological properties, including, anti-inflammatory, immunomodulatory, and neuroprotective, as well as having antioxidant and anticancer activities. This study evaluated the effects and mechanisms of RA in two racially different tripl...

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Veröffentlicht in:	European journal of pharmacology 2020-10, Vol.885, p.173419-173419, Article 173419
Hauptverfasser:	Messeha, Samia S., Zarmouh, Najla O., Asiri, Abrar, Soliman, Karam F.A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic Agents, Phytogenic - pharmacology Apoptosis Apoptosis - drug effects Apoptosis Regulatory Proteins - antagonists & inhibitors Cell cycle Cell Cycle - drug effects Cell Cycle Proteins - antagonists & inhibitors Cell Line, Tumor Cell Survival Cinnamates - pharmacology Depsides - pharmacology Female Gene expression Gene Expression Regulation, Neoplastic - drug effects Humans Membrane Proteins - antagonists & inhibitors Osteoprotegerin - antagonists & inhibitors Proto-Oncogene Proteins - antagonists & inhibitors Receptors, Tumor Necrosis Factor, Member 25 - antagonists & inhibitors Rosmarinic Rosmarinic Acid Triple Negative Breast Neoplasms - drug therapy Triple-negative breast cancer
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