The Effects of Weak and Strong CYP3A Induction by Rifampicin on the Pharmacokinetics of Five Progestins and Ethinylestradiol Compared to Midazolam

It is known that co‐administration of CYP3A inducers may decrease the effectiveness of oral contraceptives containing progestins as mono‐preparations or combined with ethinylestradiol. In a randomized clinical drug‐drug interaction study, we investigated the effects of CYP3A induction on the pharmac...

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Veröffentlicht in:	Clinical pharmacology and therapeutics 2020-10, Vol.108 (4), p.798-807
Hauptverfasser:	Wiesinger, Herbert, Klein, Stefan, Rottmann, Antje, Nowotny, Bettina, Riecke, Kai, Gashaw, Isabella, Brudny‐Klöppel, Margarete, Fricke, Robert, Höchel, Joachim, Friedrich, Christian
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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