Identification of novel mutations in SARS-COV-2 isolates from Turkey

SARS-CoV-2 was first detected in the city of Wuhan, Hubei Province, China. In this study, we identified 11 unique mutations in viral SARS-COV-2 isolates from Turkey. Nine of them cause structural alterations in the S protein, nsp2, nsp3, nsp4 and nsp12 regions. The mutations identified here might ha...

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Veröffentlicht in:	Archives of virology 2020-12, Vol.165 (12), p.2937-2944
Hauptverfasser:	Rehman, Shazia, Mahmood, Tariq, Aziz, Ejaz, Batool, Riffat
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Amino Acid Substitution Betacoronavirus - classification Betacoronavirus - genetics Betacoronavirus - isolation & purification Betacoronavirus - pathogenicity Biomedical and Life Sciences Biomedicine Brief Report Clinical Laboratory Techniques - methods Coronavirus Infections - diagnosis Coronavirus Infections - epidemiology Coronavirus Infections - transmission Coronavirus Infections - virology COVID-19 COVID-19 Testing Humans Infectious Diseases Medical Microbiology Mutation Pandemics Phylogeny Pneumonia, Viral - diagnosis Pneumonia, Viral - epidemiology Pneumonia, Viral - transmission Pneumonia, Viral - virology Point Mutation SARS-CoV-2 Sequence Alignment Sequence Homology, Amino Acid Severe acute respiratory syndrome coronavirus 2 Spike Glycoprotein, Coronavirus - genetics Therapeutic applications Turkey - epidemiology Virology
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