Why is That Chin Numb? A Case of Burkitt’s Lymphoma Presenting as Numb Chin Syndrome
We report a case of numb chin syndrome (NCS) that preceded the diagnosis of Burkitt’s lymphoma (BL) and discuss our findings with emphasis on metastatic malignancies in general and BL in particular causing NCS. A 73-year-old woman presented with worsening right-sided back pain for a week along with...
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| Veröffentlicht in: | Curēus (Palo Alto, CA) CA), 2020-09, Vol.12 (9) |
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| creator | Neel, Sejal Lohana, Abhi Chand Abbasi, Zainab Madeiro, Marcos |
| description | We report a case of numb chin syndrome (NCS) that preceded the diagnosis of Burkitt’s lymphoma (BL) and discuss our findings with emphasis on metastatic malignancies in general and BL in particular causing NCS. A 73-year-old woman presented with worsening right-sided back pain for a week along with right-sided leg weakness and a progressive thigh and perianal numbness. She reported numbness of the chin which started two weeks prior. MRI showed compression of the cauda equina which was highly suggestive of neoplastic process. After debulking mass surgery, biopsy of the tissue from spine revealed BL. The patient received a round of radiotherapy of spine and multiple rounds of chemotherapy. Six months later she had reoccurrence of lymphoma with metastasis and eventually passed away. Presence of NCS in the setting of an underlying malignancy indicates very poor prognosis. In appropriate clinical setting, NCS should trigger work up for an underlying malignancy. |
| doi_str_mv | 10.7759/cureus.10243 |
| format | Article |
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The patient received a round of radiotherapy of spine and multiple rounds of chemotherapy. Six months later she had reoccurrence of lymphoma with metastasis and eventually passed away. Presence of NCS in the setting of an underlying malignancy indicates very poor prognosis. In appropriate clinical setting, NCS should trigger work up for an underlying malignancy.</description><identifier>ISSN: 2168-8184</identifier><identifier>EISSN: 2168-8184</identifier><identifier>DOI: 10.7759/cureus.10243</identifier><identifier>PMID: 33042683</identifier><language>eng</language><publisher>Palo Alto: Cureus Inc</publisher><subject>Antibodies ; Biopsy ; Blood ; Bone marrow ; Breast cancer ; Cancer therapies ; Case reports ; Chemotherapy ; Creatinine ; Disease ; Hematology ; Hepatitis B ; Hospitals ; Internal Medicine ; Laboratories ; Lymphoma ; Medical imaging ; Metastasis ; Multiple sclerosis ; Oncology ; Pain ; Pathology ; Proteins ; Staphylococcus infections ; Trauma ; Uric acid ; Urinary retention</subject><ispartof>Curēus (Palo Alto, CA), 2020-09, Vol.12 (9)</ispartof><rights>Copyright © 2020, Neel et al. This work is published under http://creativecommons.org/licenses/by/3.0/ (the “License”). 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A Case of Burkitt’s Lymphoma Presenting as Numb Chin Syndrome</title><title>Curēus (Palo Alto, CA)</title><description>We report a case of numb chin syndrome (NCS) that preceded the diagnosis of Burkitt’s lymphoma (BL) and discuss our findings with emphasis on metastatic malignancies in general and BL in particular causing NCS. A 73-year-old woman presented with worsening right-sided back pain for a week along with right-sided leg weakness and a progressive thigh and perianal numbness. She reported numbness of the chin which started two weeks prior. MRI showed compression of the cauda equina which was highly suggestive of neoplastic process. After debulking mass surgery, biopsy of the tissue from spine revealed BL. The patient received a round of radiotherapy of spine and multiple rounds of chemotherapy. Six months later she had reoccurrence of lymphoma with metastasis and eventually passed away. Presence of NCS in the setting of an underlying malignancy indicates very poor prognosis. 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| subjects | Antibodies Biopsy Blood Bone marrow Breast cancer Cancer therapies Case reports Chemotherapy Creatinine Disease Hematology Hepatitis B Hospitals Internal Medicine Laboratories Lymphoma Medical imaging Metastasis Multiple sclerosis Oncology Pain Pathology Proteins Staphylococcus infections Trauma Uric acid Urinary retention |
| title | Why is That Chin Numb? A Case of Burkitt’s Lymphoma Presenting as Numb Chin Syndrome |
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