Impact of Lifestyles (Diet and Exercise) on Vascular Health: Oxidative Stress and Endothelial Function
Healthy lifestyle and diet are associated with significant reduction in risk of obesity, type 2 diabetes, and cardiovascular diseases. Oxidative stress and the imbalance between prooxidants and antioxidants are linked to cardiovascular and metabolic diseases. Changes in antioxidant capacity of the b...
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description | Healthy lifestyle and diet are associated with significant reduction in risk of obesity, type 2 diabetes, and cardiovascular diseases. Oxidative stress and the imbalance between prooxidants and antioxidants are linked to cardiovascular and metabolic diseases. Changes in antioxidant capacity of the body may lead to oxidative stress and vascular dysfunction. Diet is an important source of antioxidants, while exercise offers many health benefits as well. Recent findings have evidenced that diet and physical factors are correlated to oxidative stress. Diet and physical factors have debatable roles in modulating oxidative stress and effects on the endothelium. Since endothelium and oxidative stress play critical roles in cardiovascular and metabolic diseases, dietary and physical factors could have significant implications on prevention of the diseases. This review is aimed at summarizing the current knowledge on the impact of diet manipulation and physical factors on endothelium and oxidative stress, focusing on cardiovascular and metabolic diseases. We discuss the friend-and-foe role of dietary modification (including different diet styles, calorie restriction, and nutrient supplementation) on endothelium and oxidative stress, as well as the potential benefits and concerns of physical activity and exercise on endothelium and oxidative stress. A fine balance between oxidative stress and antioxidants is important for normal functions in the cells and interfering with this balance may lead to unfavorable effects. Further studies are needed to identify the best diet composition and exercise intensity. |
doi_str_mv | 10.1155/2020/1496462 |
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C. ; Xia, Ning ; Li, Huige</creator><contributor>Sutkowska, Edyta ; Edyta Sutkowska</contributor><creatorcontrib>Man, Andy W. C. ; Xia, Ning ; Li, Huige ; Sutkowska, Edyta ; Edyta Sutkowska</creatorcontrib><description>Healthy lifestyle and diet are associated with significant reduction in risk of obesity, type 2 diabetes, and cardiovascular diseases. Oxidative stress and the imbalance between prooxidants and antioxidants are linked to cardiovascular and metabolic diseases. Changes in antioxidant capacity of the body may lead to oxidative stress and vascular dysfunction. Diet is an important source of antioxidants, while exercise offers many health benefits as well. Recent findings have evidenced that diet and physical factors are correlated to oxidative stress. Diet and physical factors have debatable roles in modulating oxidative stress and effects on the endothelium. Since endothelium and oxidative stress play critical roles in cardiovascular and metabolic diseases, dietary and physical factors could have significant implications on prevention of the diseases. This review is aimed at summarizing the current knowledge on the impact of diet manipulation and physical factors on endothelium and oxidative stress, focusing on cardiovascular and metabolic diseases. We discuss the friend-and-foe role of dietary modification (including different diet styles, calorie restriction, and nutrient supplementation) on endothelium and oxidative stress, as well as the potential benefits and concerns of physical activity and exercise on endothelium and oxidative stress. A fine balance between oxidative stress and antioxidants is important for normal functions in the cells and interfering with this balance may lead to unfavorable effects. Further studies are needed to identify the best diet composition and exercise intensity.</description><identifier>ISSN: 1942-0900</identifier><identifier>EISSN: 1942-0994</identifier><identifier>DOI: 10.1155/2020/1496462</identifier><identifier>PMID: 33062134</identifier><language>eng</language><publisher>Cairo, Egypt: Hindawi Publishing Corporation</publisher><subject>Animals ; Antioxidants ; Antioxidants - chemistry ; Antioxidants - metabolism ; Bioavailability ; Cardiovascular disease ; Cardiovascular diseases ; Cardiovascular Diseases - metabolism ; Cardiovascular Diseases - pathology ; Cardiovascular Diseases - prevention & control ; Cardiovascular system ; Cell growth ; Diabetes ; Diet ; Dietary supplements ; Endothelium ; Endothelium, Vascular - metabolism ; Enzymes ; Exercise ; Humans ; Hypertension ; Metabolic disorders ; Nitric oxide ; Nitric Oxide Synthase Type III - metabolism ; Obesity ; Overweight ; Oxidation ; Oxidative Stress ; Physical fitness ; Prevention ; Reactive Oxygen Species - metabolism ; Review ; Roles ; Shear stress ; Type 2 diabetes</subject><ispartof>Oxidative medicine and cellular longevity, 2020, Vol.2020 (2020), p.1-22</ispartof><rights>Copyright © 2020 Andy W. C. Man et al.</rights><rights>COPYRIGHT 2020 John Wiley & Sons, Inc.</rights><rights>Copyright © 2020 Andy W. C. Man et al. This is an open access article distributed under the Creative Commons Attribution License (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. https://creativecommons.org/licenses/by/4.0</rights><rights>Copyright © 2020 Andy W. C. 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C.</creatorcontrib><creatorcontrib>Xia, Ning</creatorcontrib><creatorcontrib>Li, Huige</creatorcontrib><title>Impact of Lifestyles (Diet and Exercise) on Vascular Health: Oxidative Stress and Endothelial Function</title><title>Oxidative medicine and cellular longevity</title><addtitle>Oxid Med Cell Longev</addtitle><description>Healthy lifestyle and diet are associated with significant reduction in risk of obesity, type 2 diabetes, and cardiovascular diseases. Oxidative stress and the imbalance between prooxidants and antioxidants are linked to cardiovascular and metabolic diseases. Changes in antioxidant capacity of the body may lead to oxidative stress and vascular dysfunction. Diet is an important source of antioxidants, while exercise offers many health benefits as well. Recent findings have evidenced that diet and physical factors are correlated to oxidative stress. Diet and physical factors have debatable roles in modulating oxidative stress and effects on the endothelium. Since endothelium and oxidative stress play critical roles in cardiovascular and metabolic diseases, dietary and physical factors could have significant implications on prevention of the diseases. This review is aimed at summarizing the current knowledge on the impact of diet manipulation and physical factors on endothelium and oxidative stress, focusing on cardiovascular and metabolic diseases. We discuss the friend-and-foe role of dietary modification (including different diet styles, calorie restriction, and nutrient supplementation) on endothelium and oxidative stress, as well as the potential benefits and concerns of physical activity and exercise on endothelium and oxidative stress. A fine balance between oxidative stress and antioxidants is important for normal functions in the cells and interfering with this balance may lead to unfavorable effects. 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C.</au><au>Xia, Ning</au><au>Li, Huige</au><au>Sutkowska, Edyta</au><au>Edyta Sutkowska</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Impact of Lifestyles (Diet and Exercise) on Vascular Health: Oxidative Stress and Endothelial Function</atitle><jtitle>Oxidative medicine and cellular longevity</jtitle><addtitle>Oxid Med Cell Longev</addtitle><date>2020</date><risdate>2020</risdate><volume>2020</volume><issue>2020</issue><spage>1</spage><epage>22</epage><pages>1-22</pages><issn>1942-0900</issn><eissn>1942-0994</eissn><abstract>Healthy lifestyle and diet are associated with significant reduction in risk of obesity, type 2 diabetes, and cardiovascular diseases. Oxidative stress and the imbalance between prooxidants and antioxidants are linked to cardiovascular and metabolic diseases. Changes in antioxidant capacity of the body may lead to oxidative stress and vascular dysfunction. 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subjects | Animals Antioxidants Antioxidants - chemistry Antioxidants - metabolism Bioavailability Cardiovascular disease Cardiovascular diseases Cardiovascular Diseases - metabolism Cardiovascular Diseases - pathology Cardiovascular Diseases - prevention & control Cardiovascular system Cell growth Diabetes Diet Dietary supplements Endothelium Endothelium, Vascular - metabolism Enzymes Exercise Humans Hypertension Metabolic disorders Nitric oxide Nitric Oxide Synthase Type III - metabolism Obesity Overweight Oxidation Oxidative Stress Physical fitness Prevention Reactive Oxygen Species - metabolism Review Roles Shear stress Type 2 diabetes |
title | Impact of Lifestyles (Diet and Exercise) on Vascular Health: Oxidative Stress and Endothelial Function |
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