Efficacy and Safety of Hydroxychloroquine vs Placebo for Pre-exposure SARS-CoV-2 Prophylaxis Among Health Care Workers: A Randomized Clinical Trial

IMPORTANCE: Health care workers (HCWs) caring for patients with coronavirus disease 2019 (COVID-19) are at risk of exposure to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Currently, to our knowledge, there is no effective pharmacologic prophylaxis for individuals at risk. OBJECTIVE...

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Veröffentlicht in:	Archives of internal medicine (1960) 2021-02, Vol.181 (2), p.195-202
Hauptverfasser:	Abella, Benjamin S, Jolkovsky, Eliana L, Biney, Barbara T, Uspal, Julie E, Hyman, Matthew C, Frank, Ian, Hensley, Scott E, Gill, Saar, Vogl, Dan T, Maillard, Ivan, Babushok, Daria V, Huang, Alexander C, Nasta, Sunita D, Walsh, Jennifer C, Wiletyo, E. Paul, Gimotty, Phyllis A, Milone, Michael C, Amaravadi, Ravi K
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Antibodies Clinical trials COVID-19 COVID-19 - drug therapy COVID-19 - epidemiology COVID-19 - prevention & control Cross Infection - prevention & control Cross Infection - virology Double-Blind Method Female Hospitals, Urban Humans Hydroxychloroquine - administration & dosage Incidence Male Medical personnel Online First Original Investigation Pennsylvania - epidemiology Personnel, Hospital Pre-Exposure Prophylaxis SARS-CoV-2 Severe acute respiratory syndrome coronavirus 2
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