Structure-Activity Relationship Analysis of Benzotriazine Analogues as HIV-1 Latency-Reversing Agents

“Shock and kill” therapeutic strategies toward HIV eradication are based on the transcriptional activation of latent HIV with a latency-reversing agent (LRA) and the consequent killing of the reactivated cell by either the cytopathic effect of HIV or an arm of the immune system. We have recently fou...

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Veröffentlicht in:Antimicrobial agents and chemotherapy 2020-07, Vol.64 (8)
Hauptverfasser: Sorensen, Eric S, Macedo, Amanda B, Resop, Rachel S, Howard, J. Natalie, Nell, Racheal, Sarabia, Indra, Newman, Daniel, Ren, Yanqin, Jones, R. Brad, Planelles, Vicente, Spivak, Adam M, Bosque, Alberto
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