Deletion of the adenosine A2A receptor increases the survival rate in a mice model of polymicrobial sepsis

We aim to investigate the role of A 2A receptor in peritonitis-related sepsis by injection of a fecal solution (FS) as a model of polymicrobial infection . C57/black J6 wild-type (WT) and A 2A -deficient mice (A 2A KO) were exposed to sepsis induced by intraperitoneal injection of a FS (FS-induced p...

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Veröffentlicht in:	Purinergic signalling 2020-09, Vol.16 (3), p.427-437
Hauptverfasser:	Meriño, Miguel, Martín, Sebastián San, Sandaña, Pedro, Herlitz, Kurt, Aguayo, Claudio, Godoy, Alejandro, Torres-Vergara, Pablo, Gonzalez, Marcelo, Troncoso, Felipe, Acurio, Jesenia, Escudero, Carlos
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomedical and Life Sciences Biomedicine Blood pressure Cancer Research Caspase-3 Human Physiology Injection Kidneys Liver Neurosciences Original Original Article Perfusion Peripheral blood Peritonitis Pharmacology/Toxicology Sepsis Survival Telemetry
Online-Zugang:	Volltext
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