Development of fully automated and ultrasensitive assays for urinary adiponectin and their application as novel biomarkers for diabetic kidney disease

Glomerular filtration rate (GFR) and urinary albumin excretion rate (UAER) are used to diagnose and classify the severity of chronic kidney disease. Total adiponectin (T-AN) and high molecular weight adiponectin (H-AN) assays were developed using the fully automated immunoassay system, HI-1000 and t...

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Veröffentlicht in:	Scientific reports 2020-09, Vol.10 (1), p.15869-15869, Article 15869
Hauptverfasser:	Watanabe, Toshihiro, Fujimoto, Yuki, Morimoto, Aya, Nishiyama, Mai, Kawai, Akinori, Okada, Seiki, Aiba, Motohiro, Kawano, Tomoharu, Kawahigashi, Mina, Ishizu, Masashi, Mori, Hiroyasu, Matsuhisa, Munehide, Hata, Akiko, Funaki, Makoto, Hashida, Seiichi
Format:	Artikel
Sprache:	eng
Schlagworte:	631/1647/664/1467 692/53 692/699/1585 692/699/2743/137 Adiponectin - chemistry Adiponectin - urine Adult Aged Automation Biomarkers - chemistry Biomarkers - urine Diabetic Nephropathies - urine Female Humanities and Social Sciences Humans Limit of Detection Male Middle Aged Molecular Weight multidisciplinary Protein Multimerization Protein Structure, Quaternary Science Science (multidisciplinary) Urinalysis - methods
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