Bariatric Surgery in the Treatment of Type 2 Diabetes
Purpose of Review We seek to characterize the impact of bariatric surgery on diabetes mellitus by recalling its history, examining the clinical data, exploring the putative mechanisms of action, and anticipating its future. Recent Findings Results of clinical trials reveal that bariatric surgery ind...
Gespeichert in:
| Veröffentlicht in: | Current diabetes reports 2019-12, Vol.19 (12), p.156-10, Article 156 |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 10 |
|---|---|
| container_issue | 12 |
| container_start_page | 156 |
| container_title | Current diabetes reports |
| container_volume | 19 |
| creator | Affinati, Alison H. Esfandiari, Nazanene H. Oral, Elif A. Kraftson, Andrew T. |
| description | Purpose of Review
We seek to characterize the impact of bariatric surgery on diabetes mellitus by recalling its history, examining the clinical data, exploring the putative mechanisms of action, and anticipating its future.
Recent Findings
Results of clinical trials reveal that bariatric surgery induces remission of diabetes in 33–90% of individuals at 1-year post-treatment versus 0–39% of medically managed. Remission rates decrease over time but remain higher in surgically treated individuals. Investigations have revealed numerous actions of surgery including effects on intestinal physiology, neuronal signaling, incretin hormone secretion, bile acid metabolism, and microbiome changes.
Summary
Bariatric surgery improves control of diabetes through both weight-dependent and weight-independent actions. These various mechanisms help explain the difference between individuals treated surgically vs. medically. They also explain differing effects of various bariatric surgery procedure types. Understanding how surgery affects diabetes will help optimize utilization of the therapy for both disease prevention and treatment. |
| doi_str_mv | 10.1007/s11892-019-1269-4 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7522929</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2322142865</sourcerecordid><originalsourceid>FETCH-LOGICAL-c470t-5050348745f5d0142cfda1b4a46ceec9b0ccc74dcdd56811886c3698a42feebb3</originalsourceid><addsrcrecordid>eNp1kUtPwzAQhC0EouXxA7igSFy4BOyNndgXJChPqRIHytlynE2bqk2KnSD13-PSUh4SJ6-0s-MZfYScMHrBKM0uPWNSQUyZihmkKuY7pM9EomIqQe1-zjzmErIeOfB-SimEK7FPegmTFEDIPhE3xlWmdZWNXjo3RreMqjpqJxiNHJp2jnUbNWU0Wi4wgui2Mjm26I_IXmlmHo837yF5vb8bDR7j4fPD0-B6GFue0TYWVNCEy4yLUhSUcbBlYVjODU8tolU5tdZmvLBFIVIZysjUJqmShkOJmOfJIbla-y66fI6FDWmcmemFq-bGLXVjKv17U1cTPW7edSYAFKhgcL4xcM1bh77V88pbnM1MjU3nNSQAIZdMRZCe_ZFOm87Vod5KxUIuUCtDtlZZ13jvsNyGYVSvoOg1FB2g6BUUzcPN6c8W24svCkEAa4EPqzpA-P76f9cPfBiWhg</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2321369299</pqid></control><display><type>article</type><title>Bariatric Surgery in the Treatment of Type 2 Diabetes</title><source>MEDLINE</source><source>SpringerNature Journals</source><creator>Affinati, Alison H. ; Esfandiari, Nazanene H. ; Oral, Elif A. ; Kraftson, Andrew T.</creator><creatorcontrib>Affinati, Alison H. ; Esfandiari, Nazanene H. ; Oral, Elif A. ; Kraftson, Andrew T.</creatorcontrib><description>Purpose of Review
We seek to characterize the impact of bariatric surgery on diabetes mellitus by recalling its history, examining the clinical data, exploring the putative mechanisms of action, and anticipating its future.
Recent Findings
Results of clinical trials reveal that bariatric surgery induces remission of diabetes in 33–90% of individuals at 1-year post-treatment versus 0–39% of medically managed. Remission rates decrease over time but remain higher in surgically treated individuals. Investigations have revealed numerous actions of surgery including effects on intestinal physiology, neuronal signaling, incretin hormone secretion, bile acid metabolism, and microbiome changes.
Summary
Bariatric surgery improves control of diabetes through both weight-dependent and weight-independent actions. These various mechanisms help explain the difference between individuals treated surgically vs. medically. They also explain differing effects of various bariatric surgery procedure types. Understanding how surgery affects diabetes will help optimize utilization of the therapy for both disease prevention and treatment.</description><identifier>ISSN: 1534-4827</identifier><identifier>ISSN: 1539-0829</identifier><identifier>EISSN: 1539-0829</identifier><identifier>DOI: 10.1007/s11892-019-1269-4</identifier><identifier>PMID: 31802258</identifier><language>eng</language><publisher>New York: Springer US</publisher><subject>Bariatric Surgery - methods ; Diabetes ; Diabetes Mellitus, Type 2 - etiology ; Diabetes Mellitus, Type 2 - physiopathology ; Diabetes Mellitus, Type 2 - surgery ; Gastrointestinal surgery ; Humans ; Medicine ; Medicine & Public Health ; Obesity ; Obesity - complications ; Obesity - physiopathology ; Obesity - surgery ; Remission (Medicine) ; Section Editor ; Therapies and New Technologies in the Treatment of Diabetes (M Pietropaolo ; Topical Collection on Therapies and New Technologies in the Treatment of Diabetes</subject><ispartof>Current diabetes reports, 2019-12, Vol.19 (12), p.156-10, Article 156</ispartof><rights>Springer Science+Business Media, LLC, part of Springer Nature 2019</rights><rights>Current Diabetes Reports is a copyright of Springer, (2019). All Rights Reserved.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c470t-5050348745f5d0142cfda1b4a46ceec9b0ccc74dcdd56811886c3698a42feebb3</citedby><cites>FETCH-LOGICAL-c470t-5050348745f5d0142cfda1b4a46ceec9b0ccc74dcdd56811886c3698a42feebb3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s11892-019-1269-4$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s11892-019-1269-4$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>230,314,780,784,885,27924,27925,41488,42557,51319</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/31802258$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Affinati, Alison H.</creatorcontrib><creatorcontrib>Esfandiari, Nazanene H.</creatorcontrib><creatorcontrib>Oral, Elif A.</creatorcontrib><creatorcontrib>Kraftson, Andrew T.</creatorcontrib><title>Bariatric Surgery in the Treatment of Type 2 Diabetes</title><title>Current diabetes reports</title><addtitle>Curr Diab Rep</addtitle><addtitle>Curr Diab Rep</addtitle><description>Purpose of Review
We seek to characterize the impact of bariatric surgery on diabetes mellitus by recalling its history, examining the clinical data, exploring the putative mechanisms of action, and anticipating its future.
Recent Findings
Results of clinical trials reveal that bariatric surgery induces remission of diabetes in 33–90% of individuals at 1-year post-treatment versus 0–39% of medically managed. Remission rates decrease over time but remain higher in surgically treated individuals. Investigations have revealed numerous actions of surgery including effects on intestinal physiology, neuronal signaling, incretin hormone secretion, bile acid metabolism, and microbiome changes.
Summary
Bariatric surgery improves control of diabetes through both weight-dependent and weight-independent actions. These various mechanisms help explain the difference between individuals treated surgically vs. medically. They also explain differing effects of various bariatric surgery procedure types. Understanding how surgery affects diabetes will help optimize utilization of the therapy for both disease prevention and treatment.</description><subject>Bariatric Surgery - methods</subject><subject>Diabetes</subject><subject>Diabetes Mellitus, Type 2 - etiology</subject><subject>Diabetes Mellitus, Type 2 - physiopathology</subject><subject>Diabetes Mellitus, Type 2 - surgery</subject><subject>Gastrointestinal surgery</subject><subject>Humans</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Obesity</subject><subject>Obesity - complications</subject><subject>Obesity - physiopathology</subject><subject>Obesity - surgery</subject><subject>Remission (Medicine)</subject><subject>Section Editor</subject><subject>Therapies and New Technologies in the Treatment of Diabetes (M Pietropaolo</subject><subject>Topical Collection on Therapies and New Technologies in the Treatment of Diabetes</subject><issn>1534-4827</issn><issn>1539-0829</issn><issn>1539-0829</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNp1kUtPwzAQhC0EouXxA7igSFy4BOyNndgXJChPqRIHytlynE2bqk2KnSD13-PSUh4SJ6-0s-MZfYScMHrBKM0uPWNSQUyZihmkKuY7pM9EomIqQe1-zjzmErIeOfB-SimEK7FPegmTFEDIPhE3xlWmdZWNXjo3RreMqjpqJxiNHJp2jnUbNWU0Wi4wgui2Mjm26I_IXmlmHo837yF5vb8bDR7j4fPD0-B6GFue0TYWVNCEy4yLUhSUcbBlYVjODU8tolU5tdZmvLBFIVIZysjUJqmShkOJmOfJIbla-y66fI6FDWmcmemFq-bGLXVjKv17U1cTPW7edSYAFKhgcL4xcM1bh77V88pbnM1MjU3nNSQAIZdMRZCe_ZFOm87Vod5KxUIuUCtDtlZZ13jvsNyGYVSvoOg1FB2g6BUUzcPN6c8W24svCkEAa4EPqzpA-P76f9cPfBiWhg</recordid><startdate>20191201</startdate><enddate>20191201</enddate><creator>Affinati, Alison H.</creator><creator>Esfandiari, Nazanene H.</creator><creator>Oral, Elif A.</creator><creator>Kraftson, Andrew T.</creator><general>Springer US</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20191201</creationdate><title>Bariatric Surgery in the Treatment of Type 2 Diabetes</title><author>Affinati, Alison H. ; Esfandiari, Nazanene H. ; Oral, Elif A. ; Kraftson, Andrew T.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c470t-5050348745f5d0142cfda1b4a46ceec9b0ccc74dcdd56811886c3698a42feebb3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>Bariatric Surgery - methods</topic><topic>Diabetes</topic><topic>Diabetes Mellitus, Type 2 - etiology</topic><topic>Diabetes Mellitus, Type 2 - physiopathology</topic><topic>Diabetes Mellitus, Type 2 - surgery</topic><topic>Gastrointestinal surgery</topic><topic>Humans</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Obesity</topic><topic>Obesity - complications</topic><topic>Obesity - physiopathology</topic><topic>Obesity - surgery</topic><topic>Remission (Medicine)</topic><topic>Section Editor</topic><topic>Therapies and New Technologies in the Treatment of Diabetes (M Pietropaolo</topic><topic>Topical Collection on Therapies and New Technologies in the Treatment of Diabetes</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Affinati, Alison H.</creatorcontrib><creatorcontrib>Esfandiari, Nazanene H.</creatorcontrib><creatorcontrib>Oral, Elif A.</creatorcontrib><creatorcontrib>Kraftson, Andrew T.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Current diabetes reports</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Affinati, Alison H.</au><au>Esfandiari, Nazanene H.</au><au>Oral, Elif A.</au><au>Kraftson, Andrew T.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Bariatric Surgery in the Treatment of Type 2 Diabetes</atitle><jtitle>Current diabetes reports</jtitle><stitle>Curr Diab Rep</stitle><addtitle>Curr Diab Rep</addtitle><date>2019-12-01</date><risdate>2019</risdate><volume>19</volume><issue>12</issue><spage>156</spage><epage>10</epage><pages>156-10</pages><artnum>156</artnum><issn>1534-4827</issn><issn>1539-0829</issn><eissn>1539-0829</eissn><abstract>Purpose of Review
We seek to characterize the impact of bariatric surgery on diabetes mellitus by recalling its history, examining the clinical data, exploring the putative mechanisms of action, and anticipating its future.
Recent Findings
Results of clinical trials reveal that bariatric surgery induces remission of diabetes in 33–90% of individuals at 1-year post-treatment versus 0–39% of medically managed. Remission rates decrease over time but remain higher in surgically treated individuals. Investigations have revealed numerous actions of surgery including effects on intestinal physiology, neuronal signaling, incretin hormone secretion, bile acid metabolism, and microbiome changes.
Summary
Bariatric surgery improves control of diabetes through both weight-dependent and weight-independent actions. These various mechanisms help explain the difference between individuals treated surgically vs. medically. They also explain differing effects of various bariatric surgery procedure types. Understanding how surgery affects diabetes will help optimize utilization of the therapy for both disease prevention and treatment.</abstract><cop>New York</cop><pub>Springer US</pub><pmid>31802258</pmid><doi>10.1007/s11892-019-1269-4</doi><tpages>10</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1534-4827 |
| ispartof | Current diabetes reports, 2019-12, Vol.19 (12), p.156-10, Article 156 |
| issn | 1534-4827 1539-0829 1539-0829 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7522929 |
| source | MEDLINE; SpringerNature Journals |
| subjects | Bariatric Surgery - methods Diabetes Diabetes Mellitus, Type 2 - etiology Diabetes Mellitus, Type 2 - physiopathology Diabetes Mellitus, Type 2 - surgery Gastrointestinal surgery Humans Medicine Medicine & Public Health Obesity Obesity - complications Obesity - physiopathology Obesity - surgery Remission (Medicine) Section Editor Therapies and New Technologies in the Treatment of Diabetes (M Pietropaolo Topical Collection on Therapies and New Technologies in the Treatment of Diabetes |
| title | Bariatric Surgery in the Treatment of Type 2 Diabetes |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-27T15%3A35%3A09IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Bariatric%20Surgery%20in%20the%20Treatment%20of%20Type%202%20Diabetes&rft.jtitle=Current%20diabetes%20reports&rft.au=Affinati,%20Alison%20H.&rft.date=2019-12-01&rft.volume=19&rft.issue=12&rft.spage=156&rft.epage=10&rft.pages=156-10&rft.artnum=156&rft.issn=1534-4827&rft.eissn=1539-0829&rft_id=info:doi/10.1007/s11892-019-1269-4&rft_dat=%3Cproquest_pubme%3E2322142865%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2321369299&rft_id=info:pmid/31802258&rfr_iscdi=true |