E-cadherin Is an Additional Immunological Target for Pemphigus Autoantibodies

Pemphigus foliaceus (PF) and pemphigus vulgaris (PV) are autoimmune blistering diseases characterized by autoantibodies against desmoglein (Dsg)1 and Dsg3, respectively. The role of classical cadherins as immunological targets of pemphigus autoantibodies is unknown. In this study, we tested the reac...

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Veröffentlicht in:	Journal of investigative dermatology 2008-07, Vol.128 (7), p.1710-1718
Hauptverfasser:	Evangelista, Flor, Dasher, David A., Diaz, Luis A., Prisayanh, Phillip S., Li, Ning
Format:	Artikel
Sprache:	eng
Schlagworte:	Autoantibodies Autoantibodies - blood Autoantibodies - immunology Baculoviridae - genetics Biological and medical sciences Bullous diseases of the skin Cadherin Cadherins - immunology Cross Reactions Dermatology Desmoglein 1 - immunology desmoglein 3 Desmoglein 3 - immunology E-Cadherin Enzyme-Linked Immunosorbent Assay Fluorescent Antibody Technique, Indirect Humans Immunoblotting Immunofluorescence Immunoglobulin G Immunoglobulin G - blood Immunoprecipitation Immunoreactivity Internet Medical sciences Pemphigus - immunology Pemphigus foliaceus pemphigus vulgaris Recombinant Proteins - immunology
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