KCNQ1OT1 contributes to sorafenib resistance and programmed death‑ligand‑1‑mediated immune escape via sponging miR‑506 in hepatocellular carcinoma cells

Drug resistance and immune escape of tumor cells severely compromise the treatment efficiency of hepatocellular carcinoma (HCC). Long non-coding RNA KCNQ1 overlapping transcript 1 (IncRNA KCNQIOTI) has been shown to be involved in drug resistance in several cancers. The aim of the present study was...

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Veröffentlicht in:	International journal of molecular medicine 2020-11, Vol.46 (5), p.1794-1804
Hauptverfasser:	Zhang, Junli, Zhao, Xiaohui, Ma, Xiaojuan, Yuan, Zengyan, Hu, Miao
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies Apoptosis Biotechnology Cancer metastasis Cancer treatment Cell adhesion & migration Disease susceptibility Drug resistance Enzyme-linked immunosorbent assay Gene expression Hepatocellular carcinoma Inhibitor drugs Investigations Ligands Liver cancer Medical prognosis Metastasis MicroRNAs Photographic industry Proteins Reagents RNA Science Scientific equipment industry Sorafenib T cells Targeted cancer therapy Thyroid cancer
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