The role of sphingosine 1‐phosphate and its receptors in cardiovascular diseases

There are many different types of cardiovascular diseases, which impose a huge economic burden due to their extremely high mortality rates, so it is necessary to explore the underlying mechanisms to achieve better supportive and curative care outcomes. Sphingosine 1‐phosphate (S1P) is a bioactive li...

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Veröffentlicht in:	Journal of cellular and molecular medicine 2020-09, Vol.24 (18), p.10290-10301
Hauptverfasser:	Ouyang, Jie, Shu, Zhihao, Chen, Shuhua, Xiang, Hong, Lu, Hongwei
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apoptosis Atherosclerosis Autocrine signalling Biosynthesis Blood platelets Cardiovascular disease Cardiovascular diseases Cardiovascular Diseases - metabolism Cardiovascular system Cell surface Circulatory system Ejection fraction Endoplasmic reticulum Enzymes Heart attacks Heart failure Heart rate Humans Ischemia Kinases Lysophospholipids - biosynthesis Lysophospholipids - metabolism Models, Biological Paracrine signalling Phosphatase Phosphorylation Plasma Review Reviews Signal Transduction Sphingosine - analogs & derivatives Sphingosine - biosynthesis Sphingosine - metabolism Sphingosine 1-phosphate sphingosine 1‐phosphate receptor Sphingosine-1-Phosphate Receptors - metabolism Stem cells
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