Protective effects of isoquercitrin on streptozotocin‐induced neurotoxicity

Alzheimer's disease (AD) is characterized by irreversible and progressive memory loss and has no effective treatment. Recently, many small molecule nature products have been identified with neuroprotective functions and shown beneficial effects to AD patients. In the current study, we thus perf...

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Veröffentlicht in:	Journal of cellular and molecular medicine 2020-09, Vol.24 (18), p.10458-10467
Hauptverfasser:	Chen, Lei, Feng, Peimin, Peng, Anjiao, Qiu, Xiangmiao, Lai, Wanling, Zhang, Lin, Li, Wanling
Format:	Artikel
Sprache:	eng
Schlagworte:	Acids Alzheimer's disease Animal cognition Animals Antibodies Apoptosis Axonogenesis Biological Products - pharmacology Biological Products - therapeutic use Brain - drug effects Brain - pathology Brain research Cell Death - drug effects Cell Differentiation - drug effects Cell Line, Tumor Cognitive ability Cytotoxicity Flavonoids Flow cytometry Hippocampus isoquercitrin Laboratory animals Male Mice Mitochondria Mitochondria - drug effects Mitochondria - pathology mitochondrial function neurite outgrowth Neurodegeneration Neurodegenerative diseases Neuroprotection Neuroprotective Agents - pharmacology Neuroprotective Agents - therapeutic use Neurotoxicity Neurotoxicity Syndromes - drug therapy Oral administration Original Oxidative stress Oxidative Stress - drug effects Pathogenesis Proteins Quercetin - analogs & derivatives Quercetin - pharmacology Quercetin - therapeutic use Rats, Wistar Rodents Streptozocin streptozotocin
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