Isosteviol sodium protects the cardiomyocyte response associated with the SIRT1/PGC‐1α pathway

Cardiomyocyte dysfunction is attributed to excess oxidative damage, but the molecular pathways involved in this process have not been completely elucidated. Evidence indicates that isosteviol sodium (STVNa) has cardioprotective effects. We therefore aimed to identify the effect of STVNa on cardiomyo...

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Veröffentlicht in:	Journal of cellular and molecular medicine 2020-09, Vol.24 (18), p.10866-10875
Hauptverfasser:	Mei, Ying, Liu, Bo, Su, Hao, Zhang, Hao, Liu, Fei, Ke, Qingjin, Sun, Xiaoou, Tan, Wen
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies cardiomyocyte dysfunction Cardiomyocytes Cell culture Cells Dehydrogenases Deoxyribonucleic acid Design DNA Fluorides Glucose Hypertrophy isosteviol sodium Kinases Metabolism Mitochondria Mitochondrial DNA Original PGC‐1α Proteins Signal transduction SIRT1 SIRT1 protein Sodium
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