Enhanced Contextual Fear Memory and Elevated Astroglial Glutamate Synthase Activity in Hippocampal CA1 BChE shRNA Knockdown Mice

Butyrylcholinesterase (BChE) efficiently hydrolyzes acetylcholine (ACh) at high concentrations when acetylcholinesterase (AChE) is substrate-inhibited. Recent studies have shown that BChE also has a function that is independent of ACh, but it has not been fully explored. Low BChE expression is accom...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Frontiers in psychiatry 2020-09, Vol.11, p.564843-564843
Hauptverfasser:	Chen, Si, Lin, Zhengdong, Tan, Kai-Leng, Chen, Risheng, Su, Wenfang, Zhao, Haishan, Tan, Qiwen, Tan, Wen
Format:	Artikel
Sprache:	eng
Schlagworte:	acetylcholine astrocyte butyrylcholinesterase contextual fear memory hippocampus CA1 posttraumatic stress disorder Psychiatry
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!