Phosphatidylinositol(4,5)bisphosphate: diverse functions at the plasma membrane

Phosphatidylinositol(4,5) bisphosphate (PI(4,5)P2) has become a major focus in biochemistry, cell biology and physiology owing to its diverse functions at the plasma membrane. As a result, the functions of PI(4,5)P2 can be explored in two separate and distinct roles - as a substrate for phospholipas...

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Veröffentlicht in:	Essays in biochemistry 2020-09, Vol.64 (3), p.513-531
Hauptverfasser:	Katan, Matilda, Cockcroft, Shamshad
Format:	Artikel
Sprache:	eng
Schlagworte:	Actin Cytoskeleton - metabolism Animals Cell Membrane - metabolism Diglycerides - metabolism Endocytosis - physiology Exocytosis - physiology Glycerophospholipids - metabolism Humans Hydrolysis Inositol 1,4,5-Trisphosphate - metabolism Ion Channels - metabolism Phosphatidylinositol 3-Kinases - metabolism Phosphatidylinositol 4,5-Diphosphate - chemistry Phosphatidylinositol 4,5-Diphosphate - metabolism Review Signal Transduction - physiology Signaling Type C Phospholipases - metabolism
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