$Aldosterone up-regulates voltage-gated potassium currents and NKCC1 protein membrane fractions$

Aldosterone up-regulates voltage-gated potassium currents and NKCC1 protein membrane fractions

Na + –K + –2Cl − Cotransporter (NKCC1) is a protein that aids in the active transport of sodium, potassium, and chloride ions across cell membranes. It has been shown that long-term systemic treatment with aldosterone (ALD) can enhance NKCC1 protein expression and activity in the aging cochlea resul...

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Veröffentlicht in:	Scientific reports 2020-09, Vol.10 (1), p.15604, Article 15604
Hauptverfasser:	Bazard, Parveen, Ding, Bo, Chittam, Harish K., Zhu, Xiaoxia, Parks, Thomas A., Taylor-Clark, Thomas E., Bhethanabotla, Venkat R., Frisina, Robert D., Walton, Joseph P.
Format:	Artikel
Sprache:	eng
Schlagworte:	631/443 692/4017 Aldosterone - pharmacology Cell Membrane - metabolism Gene Expression Regulation - drug effects Humanities and Social Sciences Humans Ion Channel Gating - drug effects multidisciplinary Neuroblastoma - metabolism Neuroblastoma - pathology Potassium - metabolism Receptors, Mineralocorticoid - metabolism Science Science (multidisciplinary) Solute Carrier Family 12, Member 2 - metabolism Tumor Cells, Cultured Up-Regulation
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