CD8+ T cells are increased in the subventricular zone with physiological and pathological aging

Age‐related cognitive decline and neurodegenerative diseases are associated with less functional neurogenic niches. It has been recently shown that aged subventricular zone (SVZ) suffers an infiltration of T cells, which affects neural stem cell activity in mice. Whether this occurs in human neuroge...

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Veröffentlicht in:	Aging cell 2020-09, Vol.19 (9), p.e13198-n/a
Hauptverfasser:	Moreno‐Valladares, Manuel, Moreno‐Cugnon, Leire, Silva, Tulio Mateo, Garcés, Juan Pablo, Saenz‐Antoñanzas, Ander, Álvarez‐Satta, María, Matheu, Ander
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Aging Antigens Brain CD3 antigen CD8 antigen CD8+ cells Cognitive ability Cytoplasm Cytotoxicity Dentate gyrus Geriatrics Infiltration Lymphocytes Lymphocytes T Medical research Medicine, Experimental Morphology Neural stem cells Neurodegenerative diseases Neurogenesis Original Physiological aspects Physiology Stem cells Subventricular zone T cells T‐cell infiltration
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