Posttranscriptional regulation of thiamin transporter-1 expression by microRNA-200a-3p in pancreatic acinar cells

The water-soluble vitamin B1 (thiamin) plays essential roles in normal metabolism and function of all human/mammalian cells, including the pancreatic acinar cells (PACs). PACs obtain thiamin from their surrounding circulation via transport across the plasma membrane, a process that is mediated by th...

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Veröffentlicht in:	American journal of physiology: Gastrointestinal and liver physiology 2020-09, Vol.319 (3), p.G323-G332
Hauptverfasser:	Ramamoorthy, Kalidas, Anandam, Kasin Yadunandam, Yasujima, Tomoya, Srinivasan, Padmanabhan, Said, Hamid M
Format:	Artikel
Sprache:	eng
Schlagworte:	3' Untranslated regions 3' Untranslated Regions - genetics Acinar cells Acinar Cells - metabolism Animals Binding sites Gene expression Humans Mammalian cells Membrane Transport Proteins - genetics Mice MicroRNAs MicroRNAs - genetics miRNA mRNA Mutation Pancreas Pancreas - metabolism Post-transcription Primary Cell Culture RNA Processing, Post-Transcriptional - genetics Thiamine Thiamine - metabolism Transfection Vitamin B
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