DNA Repair and Signaling in Immune-Related Cancer Therapy

Cancer therapy using immune checkpoint inhibitors (ICIs) is a promising clinical strategy for patients with multiple types of cancer. The expression of programmed cell death ligand-1 (PD-L1), an immune-suppressor ligand, in cancer cells is a factor that influences the efficacy of ICI therapy, partic...

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Veröffentlicht in:	Frontiers in molecular biosciences 2020-09, Vol.7, p.205-205, Article 205
Hauptverfasser:	Kakoti, Sangeeta, Sato, Hiro, Laskar, Siddhartha, Yasuhara, Takaaki, Shibata, Atsushi
Format:	Artikel
Sprache:	eng
Schlagworte:	ataxia telangiectasia and Rad3-related ataxia-telangiectasia-mutated Biochemistry & Molecular Biology DNA repair homologous recombination immune checkpoint inhibitor Life Sciences & Biomedicine Molecular Biosciences non-homologous end joining Science & Technology
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