Impact of Extracellular Vesicle Isolation Methods on Downstream Mirna Analysis in Semen: A Comparative Study

Seminal plasma (SP) contains a unique concentration of miRNA, mostly contained in small extracellular vesicles (sEVs) such as exosomes, some of which could be clinically useful for diagnosis and/or prognosis of urogenital diseases such as prostate cancer (PCa). We optimized several exosome-EV isolat...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	International journal of molecular sciences 2020-08, Vol.21 (17), p.5949
Hauptverfasser:	Mercadal, Marina, Herrero, Carolina, López-Rodrigo, Olga, Castells, Manel, de la Fuente, Alexandre, Vigués, Francesc, Bassas, Lluís, Larriba, Sara
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Biomarkers Biomarkers, Tumor - genetics Biomarkers, Tumor - metabolism Biomarkers, Tumor - standards Blood Cell Fractionation - methods Comparative studies Diagnosis Exosomes Extracellular vesicles Extracellular Vesicles - metabolism Gene expression Humans Impact analysis Labeling Laboratories Liquid Biopsy - methods Male Methods MicroRNAs - genetics MicroRNAs - metabolism MicroRNAs - standards Middle Aged miRNA Nanoparticles Plasma Prostate cancer Prostatic Neoplasms - genetics Prostatic Neoplasms - metabolism Prostatic Neoplasms - pathology Quality Semen Semen - metabolism Ultracentrifugation Urine Vesicles
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!