Ketones Elicit Distinct Alterations in Adipose Mitochondrial Bioenergetics

The rampant growth of obesity worldwide has stimulated explosive research into human metabolism. Energy expenditure has been shown to be altered by diets differing in macronutrient composition, with low-carbohydrate, ketogenic diets eliciting a significant increase over other interventions. The cent...

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Veröffentlicht in:	International journal of molecular sciences 2020-08, Vol.21 (17), p.6255
Hauptverfasser:	Walton, Chase M, Jacobsen, Samuel M, Dallon, Blake W, Saito, Erin R, Bennett, Shantelle L H, Davidson, Lance E, Thomson, David M, Hyldahl, Robert D, Bikman, Benjamin T
Format:	Artikel
Sprache:	eng
Schlagworte:	3-Hydroxybutyric Acid - administration & dosage 3-Hydroxybutyric Acid - pharmacology 3T3-L1 Cells Adenosine Triphosphate - metabolism Adipocytes Adipocytes - cytology Adipocytes - drug effects Adipocytes - metabolism Adipose tissue Adult Animal models Animals Bioenergetics Biosynthesis Carbohydrates Cell culture Cells, Cultured Diet Electron transport Energy Energy expenditure Energy metabolism Energy Metabolism - drug effects Female Gene expression Gene Expression Profiling Gene Expression Regulation - drug effects Gene Regulatory Networks - drug effects Humans Ketones Lipids Low carbohydrate diet Male Metabolic rate Metabolism Metabolites Mice Mitochondria Mitochondria - drug effects Mitochondria - metabolism Nutrient deficiency Obesity Physiology Rats Respiration Subcutaneous Fat - drug effects Subcutaneous Fat - metabolism
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