Epiregulin promotes hair growth via EGFR‐medicated epidermal and ErbB4‐mediated dermal stimulation

Objectives EREG (epiregulin), a member of the epidermal growth factor (EGF) family, plays a role in inflammation, wound healing, normal physiology and malignancies. However, little is known about its function on hair growth. Materials and Methods Cell growth assay, QPCR and immunostaining were carri...

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Veröffentlicht in:	Cell proliferation 2020-09, Vol.53 (9), p.e12881-n/a
Hauptverfasser:	Choi, Nahyun, Kim, Won‐Serk, Oh, Sang Ho, Sung, Jong‐Hyuk
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Binding sites Cell activation Cell culture Cell Line Cell Proliferation Cycles Dermis - cytology Dermis - metabolism Epidermal Cells - cytology Epidermal Cells - metabolism Epidermal growth factor Epidermal growth factor receptors Epidermis - metabolism Epiregulin - metabolism ErbB Receptors - metabolism ErbB-2 protein Experiments Growth factors Hair Hair - growth & development Hair - metabolism Hair loss Humans Kinases Male Mice Motility Organ culture Original Phosphorylation Positive feedback Reactive oxygen species Reactive Oxygen Species - metabolism Receptor, ErbB-4 - metabolism Stimulation Wound healing
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