Human γδ T cells recognize CD1b by two distinct mechanisms

γδ T cells form an abundant part of the human cellular immune system, where they respond to tissue damage, infection, and cancer. The spectrum of known molecular targets recognized by Vδ1-expressing γδ T cells is becoming increasingly diverse. Here we describe human γδ T cells that recognize CD1b, a...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2020-09, Vol.117 (37), p.22944-22952
Hauptverfasser:	Reijneveld, Josephine F., Ocampo, Tonatiuh A., Shahine, Adam, Gully, Benjamin S., Vantourout, Pierre, Hayday, Adrian C., Rossjohn, Jamie, Moody, D. Branch, Van Rhijn, Ildiko
Format:	Artikel
Sprache:	eng
Schlagworte:	Antigen Presentation Antigens Antigens, CD1 - immunology Antigens, CD1 - metabolism Biological Sciences Butyrophilin Chains Crystallography, X-Ray - methods Dendritic cells Humans Immune system Intraepithelial Lymphocytes - immunology Intraepithelial Lymphocytes - metabolism Intraepithelial Lymphocytes - physiology Lipids Lipids - immunology Lymphocyte Activation - immunology Lymphocytes Lymphocytes T Major histocompatibility complex Models, Molecular Monocytes Monocytes - metabolism Proteins Receptors T cell receptors T-Lymphocytes - immunology Target recognition
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!