Novel combination therapy for melanoma induces apoptosis via a gap junction positive feedback mechanism

Metastatic melanoma cells overexpressing gap junctions were assayed for their ability to propagate cell death by a novel combination therapy that generates reactive oxygen species (ROS) by both 1) non-thermal plasma (NTP) and 2) tirapazamine (TPZ) under hypoxic conditions. Results demonstrate additi...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Oncotarget 2020-09, Vol.11 (37), p.3443-3458
Hauptverfasser:	Bagati, Archis, Hutcherson, Timothy C., Koch, Zethan, Pechette, Joseph, Dianat, Hossein, Higley, Cory, Chiu, Lisa, Song, Yesul, Shah, Jay, Chazen, Elana, Nicolais, Andrew, Casey, Peter, Thompson, Kyle, Burke, Kevin, Nikiforov, Mikhail A., Zirnheld, Jennifer, Zucker, Shoshanna N.
Format:	Artikel
Sprache:	eng
Schlagworte:	Research Paper
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!