Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), a newly emerged pathogen: an overview
ABSTRACT Coronavirus disease 2019 (COVID-19) is a viral pneumonia, responsible for the recent pandemic, and originated from Wuhan, China, in December 2019. The causative agent of the outbreak was identified as coronavirus and designated as severe acute respiratory syndrome coronavirus 2 (SARS- CoV-2...
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| creator | Rathore, Jitendra Singh Ghosh, Chaitali |
| description | ABSTRACT
Coronavirus disease 2019 (COVID-19) is a viral pneumonia, responsible for the recent pandemic, and originated from Wuhan, China, in December 2019. The causative agent of the outbreak was identified as coronavirus and designated as severe acute respiratory syndrome coronavirus 2 (SARS- CoV-2). Few years back, the severe acute respiratory syndrome coronavirus (SARS- CoV) and the Middle East respiratory syndrome coronavirus (MERS-CoV) were reported to be highly pathogenic and caused severe infections in humans. In the current situation SARS-CoV-2 has become the third highly pathogenic coronavirus that is responsible for the present outbreak in human population. At the time of this review, there were more than 14 007 791 confirmed COVID-19 patients which associated with over 597 105 deaths in more then 216 countries across the globe (as reported by World Health Organization). In this review we have discussed about SARS-CoV, MERS-CoV and SARC-CoV-2, their reservoirs, role of spike proteins and immunogenicity. We have also covered the diagnosis, therapeutics and vaccine status of SARS-CoV-2.
An updated review of emerging cornoaviruses SARS-CoV, MERS-CoV, SARS-CoV-2, and potential therapeutic and preventive approaches. |
| doi_str_mv | 10.1093/femspd/ftaa042 |
| format | Article |
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Coronavirus disease 2019 (COVID-19) is a viral pneumonia, responsible for the recent pandemic, and originated from Wuhan, China, in December 2019. The causative agent of the outbreak was identified as coronavirus and designated as severe acute respiratory syndrome coronavirus 2 (SARS- CoV-2). Few years back, the severe acute respiratory syndrome coronavirus (SARS- CoV) and the Middle East respiratory syndrome coronavirus (MERS-CoV) were reported to be highly pathogenic and caused severe infections in humans. In the current situation SARS-CoV-2 has become the third highly pathogenic coronavirus that is responsible for the present outbreak in human population. At the time of this review, there were more than 14 007 791 confirmed COVID-19 patients which associated with over 597 105 deaths in more then 216 countries across the globe (as reported by World Health Organization). In this review we have discussed about SARS-CoV, MERS-CoV and SARC-CoV-2, their reservoirs, role of spike proteins and immunogenicity. We have also covered the diagnosis, therapeutics and vaccine status of SARS-CoV-2.
An updated review of emerging cornoaviruses SARS-CoV, MERS-CoV, SARS-CoV-2, and potential therapeutic and preventive approaches.</description><identifier>ISSN: 2049-632X</identifier><identifier>EISSN: 2049-632X</identifier><identifier>DOI: 10.1093/femspd/ftaa042</identifier><identifier>PMID: 32840560</identifier><language>eng</language><publisher>United States: Oxford University Press</publisher><subject>Angiotensin-Converting Enzyme 2 ; Animals ; Antiviral Agents - therapeutic use ; Betacoronavirus - drug effects ; Betacoronavirus - genetics ; Betacoronavirus - immunology ; Causes of ; Coronaviridae ; Coronavirus Infections - drug therapy ; Coronavirus Infections - epidemiology ; Coronavirus Infections - pathology ; Coronaviruses ; COVID-19 ; Disease Reservoirs - veterinary ; Disease Reservoirs - virology ; Epidemics ; Human populations ; Humans ; Identification and classification ; Immunogenicity ; India ; International aspects ; Middle East respiratory syndrome ; Middle East Respiratory Syndrome Coronavirus - drug effects ; Middle East Respiratory Syndrome Coronavirus - genetics ; Middle East Respiratory Syndrome Coronavirus - immunology ; Mini Review ; Minireview ; Outbreaks ; Pandemics ; Peptidyl-Dipeptidase A - metabolism ; Pneumonia, Viral - drug therapy ; Pneumonia, Viral - epidemiology ; Pneumonia, Viral - pathology ; Respiratory diseases ; SARS-CoV-2 ; Severe Acute Respiratory Syndrome - drug therapy ; Severe Acute Respiratory Syndrome - epidemiology ; Severe Acute Respiratory Syndrome - pathology ; Severe acute respiratory syndrome coronavirus 2 ; Spike Glycoprotein, Coronavirus - immunology ; Spike Glycoprotein, Coronavirus - metabolism ; Viral diseases ; Zoonoses - virology</subject><ispartof>Pathogens and Disease, 2020-08, Vol.78 (6), p.1</ispartof><rights>The Author(s) 2020. Published by Oxford University Press on behalf of FEMS. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com 2020</rights><rights>FEMS 2020.</rights><rights>COPYRIGHT 2020 Oxford University Press</rights><rights>FEMS 2020. 2020</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c575t-ca35d8fd11cce900101ff6bbcae55867e40a52aecabe6d9b48b21e9ed32e18e53</citedby><cites>FETCH-LOGICAL-c575t-ca35d8fd11cce900101ff6bbcae55867e40a52aecabe6d9b48b21e9ed32e18e53</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7499575/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7499575/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,315,728,781,785,886,1605,27926,27927,53793,53795</link.rule.ids><linktorsrc>$$Uhttps://dx.doi.org/10.1093/femspd/ftaa042$$EView_record_in_Oxford_University_Press$$FView_record_in_$$GOxford_University_Press</linktorsrc><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/32840560$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Rathore, Jitendra Singh</creatorcontrib><creatorcontrib>Ghosh, Chaitali</creatorcontrib><title>Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), a newly emerged pathogen: an overview</title><title>Pathogens and Disease</title><addtitle>Pathog Dis</addtitle><description>ABSTRACT
Coronavirus disease 2019 (COVID-19) is a viral pneumonia, responsible for the recent pandemic, and originated from Wuhan, China, in December 2019. The causative agent of the outbreak was identified as coronavirus and designated as severe acute respiratory syndrome coronavirus 2 (SARS- CoV-2). Few years back, the severe acute respiratory syndrome coronavirus (SARS- CoV) and the Middle East respiratory syndrome coronavirus (MERS-CoV) were reported to be highly pathogenic and caused severe infections in humans. In the current situation SARS-CoV-2 has become the third highly pathogenic coronavirus that is responsible for the present outbreak in human population. At the time of this review, there were more than 14 007 791 confirmed COVID-19 patients which associated with over 597 105 deaths in more then 216 countries across the globe (as reported by World Health Organization). In this review we have discussed about SARS-CoV, MERS-CoV and SARC-CoV-2, their reservoirs, role of spike proteins and immunogenicity. We have also covered the diagnosis, therapeutics and vaccine status of SARS-CoV-2.
An updated review of emerging cornoaviruses SARS-CoV, MERS-CoV, SARS-CoV-2, and potential therapeutic and preventive approaches.</description><subject>Angiotensin-Converting Enzyme 2</subject><subject>Animals</subject><subject>Antiviral Agents - therapeutic use</subject><subject>Betacoronavirus - drug effects</subject><subject>Betacoronavirus - genetics</subject><subject>Betacoronavirus - immunology</subject><subject>Causes of</subject><subject>Coronaviridae</subject><subject>Coronavirus Infections - drug therapy</subject><subject>Coronavirus Infections - epidemiology</subject><subject>Coronavirus Infections - pathology</subject><subject>Coronaviruses</subject><subject>COVID-19</subject><subject>Disease Reservoirs - veterinary</subject><subject>Disease Reservoirs - virology</subject><subject>Epidemics</subject><subject>Human populations</subject><subject>Humans</subject><subject>Identification and classification</subject><subject>Immunogenicity</subject><subject>India</subject><subject>International aspects</subject><subject>Middle East respiratory syndrome</subject><subject>Middle East Respiratory Syndrome Coronavirus - 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Coronavirus disease 2019 (COVID-19) is a viral pneumonia, responsible for the recent pandemic, and originated from Wuhan, China, in December 2019. The causative agent of the outbreak was identified as coronavirus and designated as severe acute respiratory syndrome coronavirus 2 (SARS- CoV-2). Few years back, the severe acute respiratory syndrome coronavirus (SARS- CoV) and the Middle East respiratory syndrome coronavirus (MERS-CoV) were reported to be highly pathogenic and caused severe infections in humans. In the current situation SARS-CoV-2 has become the third highly pathogenic coronavirus that is responsible for the present outbreak in human population. At the time of this review, there were more than 14 007 791 confirmed COVID-19 patients which associated with over 597 105 deaths in more then 216 countries across the globe (as reported by World Health Organization). In this review we have discussed about SARS-CoV, MERS-CoV and SARC-CoV-2, their reservoirs, role of spike proteins and immunogenicity. We have also covered the diagnosis, therapeutics and vaccine status of SARS-CoV-2.
An updated review of emerging cornoaviruses SARS-CoV, MERS-CoV, SARS-CoV-2, and potential therapeutic and preventive approaches.</abstract><cop>United States</cop><pub>Oxford University Press</pub><pmid>32840560</pmid><doi>10.1093/femspd/ftaa042</doi><oa>free_for_read</oa></addata></record> |
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| ispartof | Pathogens and Disease, 2020-08, Vol.78 (6), p.1 |
| issn | 2049-632X 2049-632X |
| language | eng |
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| source | Oxford Journals Open Access Collection |
| subjects | Angiotensin-Converting Enzyme 2 Animals Antiviral Agents - therapeutic use Betacoronavirus - drug effects Betacoronavirus - genetics Betacoronavirus - immunology Causes of Coronaviridae Coronavirus Infections - drug therapy Coronavirus Infections - epidemiology Coronavirus Infections - pathology Coronaviruses COVID-19 Disease Reservoirs - veterinary Disease Reservoirs - virology Epidemics Human populations Humans Identification and classification Immunogenicity India International aspects Middle East respiratory syndrome Middle East Respiratory Syndrome Coronavirus - drug effects Middle East Respiratory Syndrome Coronavirus - genetics Middle East Respiratory Syndrome Coronavirus - immunology Mini Review Minireview Outbreaks Pandemics Peptidyl-Dipeptidase A - metabolism Pneumonia, Viral - drug therapy Pneumonia, Viral - epidemiology Pneumonia, Viral - pathology Respiratory diseases SARS-CoV-2 Severe Acute Respiratory Syndrome - drug therapy Severe Acute Respiratory Syndrome - epidemiology Severe Acute Respiratory Syndrome - pathology Severe acute respiratory syndrome coronavirus 2 Spike Glycoprotein, Coronavirus - immunology Spike Glycoprotein, Coronavirus - metabolism Viral diseases Zoonoses - virology |
| title | Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), a newly emerged pathogen: an overview |
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