Buckling of an Epithelium Growing under Spherical Confinement

Many organs are formed through folding of an epithelium. This change in shape is usually attributed to tissue heterogeneities, for example, local apical contraction. In contrast, compressive stresses have been proposed to fold a homogeneous epithelium by buckling. While buckling is an appealing mech...

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Veröffentlicht in:	Developmental cell 2020-09, Vol.54 (5), p.655-668.e6
Hauptverfasser:	Trushko, Anastasiya, Di Meglio, Ilaria, Merzouki, Aziza, Blanch-Mercader, Carles, Abuhattum, Shada, Guck, Jochen, Alessandri, Kevin, Nassoy, Pierre, Kruse, Karsten, Chopard, Bastien, Roux, Aurélien
Format:	Artikel
Sprache:	eng
Schlagworte:	3D cell culture alginate capsules Biological Physics Biomechanical Phenomena - physiology Cell Adhesion - physiology Cell Proliferation - physiology Computer Simulation Elastic Modulus - physiology epithelial monolayer Epithelium - growth & development epithelium mechanics Humans Models, Biological morphogenesis Physics
Online-Zugang:	Volltext
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