Coagulopathy signature precedes and predicts severity of end‐organ heat stroke pathology in a mouse model

Background Immune challenge is known to increase heat stroke risk, although the mechanism of this increased risk is unclear. Objectives We sought to understand the effect of immune challenge on heat stroke pathology. Patients/Methods Using a mouse model of classic heat stroke, we examined the impact...

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Veröffentlicht in:Journal of thrombosis and haemostasis 2020-08, Vol.18 (8), p.1900-1910
Hauptverfasser: Proctor, Elizabeth A., Dineen, Shauna M., Van Nostrand, Stephen C., Kuhn, Madison K., Barrett, Christopher D., Brubaker, Douglas K., Yaffe, Michael B., Lauffenburger, Douglas A., Leon, Lisa R.
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Sprache:eng
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