Characterizing the original anti‐C5 function‐blocking antibody, BB5.1, for species specificity, mode of action and interactions with C5

The work provides a mechanistic basis for the activities of this landmark antibody BB5.1, a much‐used tool that was a major impetus to the development of anti‐complement drugs for human disease. Summary The implication of complement in multiple diseases over the last 20 years has fuelled interest in...

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