Frequency‐dependent signal and noise in spectroscopic x‐ray imaging
Purpose We present a new framework for theoretical analysis of the noise power spectrum (NPS) of photon‐counting x‐ray detectors, including simple photon‐counting detectors (SPCDs) and spectroscopic x‐ray detectors (SXDs), the latter of which use multiple energy thresholds to discriminate photon ene...
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creator | Tanguay, Jesse Kim, Jinwoo Kim, Ho Kyung Iniewski, Kris Cunningham, Ian A. |
description | Purpose
We present a new framework for theoretical analysis of the noise power spectrum (NPS) of photon‐counting x‐ray detectors, including simple photon‐counting detectors (SPCDs) and spectroscopic x‐ray detectors (SXDs), the latter of which use multiple energy thresholds to discriminate photon energies.
Methods
We show that the NPS of SPCDs and SXDs, including spatio‐energetic noise correlations, is determined by the joint probability density function (PDF) of deposited photon energies, which describes the probability of recording two photons of two different energies in two different elements following a single‐photon interaction. We present an analytic expression for this joint PDF and calculate the presampling and digital NPS of CdTe SPCDs and SXDs. We calibrate our charge sharing model using the energy response of a cadmium zinc telluride (CZT) spectroscopic x‐ray detector and compare theoretical results with Monte Carlo simulations.
Results
Our analysis shows that charge sharing increases pixel signal‐to‐noise ratio (SNR), but degrades the zero‐frequency signal‐to‐noise performance of SPCDs and SXDs. In all cases considered, this degradation was greater than 10%. Comparing the presampling NPS with the sampled NPS showed that degradation in zero‐frequency performance is due to zero‐frequency noise aliasing induced by charge sharing.
Conclusions
Noise performance, including spatial and energy correlations between elements and energy bins, are described by the joint PDF of deposited energies which provides a method of determining the photon‐counting NPS, including noise‐aliasing effects and spatio‐energetic effects in spectral imaging. Our approach enables separating noise due to x‐ray interactions from that associated with sampling, consistent with cascaded systems analysis of energy‐integrating systems. Our methods can be incorporated into task‐based assessment of image quality for the design and optimization of spectroscopic x‐ray detectors. |
doi_str_mv | 10.1002/mp.14160 |
format | Article |
fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7496729</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2385708724</sourcerecordid><originalsourceid>FETCH-LOGICAL-c4100-b417c0efe87eea5ac0ffa0a276ae48c8802f0ccd932ce7425ef0c601108091c23</originalsourceid><addsrcrecordid>eNp1kEFOwzAQRS0EoqUgcQKUJZuUsePEyQYJVbQgFcEC1pbrTIpR4oS4BbLjCJyRk2BoKbBgZY389ObPJ-SQwpACsJOqGVJOE9gifcZFFHIG2TbpA2Q8ZBziHtlz7gEAkiiGXdKLGIuymIo-mYxbfFyi1d3761uODdoc7SJwZm5VGSibB7Y2DgNjA9egXrS103VjdPDi-VZ1ganU3Nj5PtkpVOnwYP0OyN34_HZ0EU6vJ5ejs2mouU8azjgVGrDAVCCqWGkoCgWKiUQhT3WaAitA6zyLmEbBWYx-TIBSSCGjmkUDcrryNstZhbn2YVtVyqb1OdpO1srIvz_W3Mt5_SQFzxLBMi84Xgva2h_uFrIyTmNZKov10kkWpbGAVDD-g2p_tWux2KyhID97l1Ujv3r36NHvWBvwu2gPhCvg2ZTY_SuSVzcr4QcWD48B</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2385708724</pqid></control><display><type>article</type><title>Frequency‐dependent signal and noise in spectroscopic x‐ray imaging</title><source>Wiley Online Library - AutoHoldings Journals</source><source>MEDLINE</source><source>Alma/SFX Local Collection</source><creator>Tanguay, Jesse ; Kim, Jinwoo ; Kim, Ho Kyung ; Iniewski, Kris ; Cunningham, Ian A.</creator><creatorcontrib>Tanguay, Jesse ; Kim, Jinwoo ; Kim, Ho Kyung ; Iniewski, Kris ; Cunningham, Ian A.</creatorcontrib><description>Purpose
We present a new framework for theoretical analysis of the noise power spectrum (NPS) of photon‐counting x‐ray detectors, including simple photon‐counting detectors (SPCDs) and spectroscopic x‐ray detectors (SXDs), the latter of which use multiple energy thresholds to discriminate photon energies.
Methods
We show that the NPS of SPCDs and SXDs, including spatio‐energetic noise correlations, is determined by the joint probability density function (PDF) of deposited photon energies, which describes the probability of recording two photons of two different energies in two different elements following a single‐photon interaction. We present an analytic expression for this joint PDF and calculate the presampling and digital NPS of CdTe SPCDs and SXDs. We calibrate our charge sharing model using the energy response of a cadmium zinc telluride (CZT) spectroscopic x‐ray detector and compare theoretical results with Monte Carlo simulations.
Results
Our analysis shows that charge sharing increases pixel signal‐to‐noise ratio (SNR), but degrades the zero‐frequency signal‐to‐noise performance of SPCDs and SXDs. In all cases considered, this degradation was greater than 10%. Comparing the presampling NPS with the sampled NPS showed that degradation in zero‐frequency performance is due to zero‐frequency noise aliasing induced by charge sharing.
Conclusions
Noise performance, including spatial and energy correlations between elements and energy bins, are described by the joint PDF of deposited energies which provides a method of determining the photon‐counting NPS, including noise‐aliasing effects and spatio‐energetic effects in spectral imaging. Our approach enables separating noise due to x‐ray interactions from that associated with sampling, consistent with cascaded systems analysis of energy‐integrating systems. Our methods can be incorporated into task‐based assessment of image quality for the design and optimization of spectroscopic x‐ray detectors.</description><identifier>ISSN: 0094-2405</identifier><identifier>EISSN: 2473-4209</identifier><identifier>DOI: 10.1002/mp.14160</identifier><identifier>PMID: 32239517</identifier><language>eng</language><publisher>United States: John Wiley and Sons Inc</publisher><subject>Cadmium Compounds ; detective quantum efficiency ; DIAGNOSTIC IMAGING (IONIZING AND NON‐IONIZING) ; dual-energy imaging ; noise power spectrum ; photon-counting ; Photons ; Quantum Dots ; spectroscopic x-ray imaging ; Tellurium ; X-Rays</subject><ispartof>Medical physics (Lancaster), 2020-07, Vol.47 (7), p.2881-2901</ispartof><rights>2020 The Authors. Medical Physics published by Wiley Periodicals LLC on behalf of American Association of Physicists in Medicineehalf of American Association of Physicists in Medicine</rights><rights>2020 The Authors. Medical Physics published by Wiley Periodicals LLC on behalf of American Association of Physicists in Medicineehalf of American Association of Physicists in Medicine.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4100-b417c0efe87eea5ac0ffa0a276ae48c8802f0ccd932ce7425ef0c601108091c23</citedby><cites>FETCH-LOGICAL-c4100-b417c0efe87eea5ac0ffa0a276ae48c8802f0ccd932ce7425ef0c601108091c23</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fmp.14160$$EPDF$$P50$$Gwiley$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fmp.14160$$EHTML$$P50$$Gwiley$$Hfree_for_read</linktohtml><link.rule.ids>230,314,776,780,881,1411,27901,27902,45550,45551</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/32239517$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Tanguay, Jesse</creatorcontrib><creatorcontrib>Kim, Jinwoo</creatorcontrib><creatorcontrib>Kim, Ho Kyung</creatorcontrib><creatorcontrib>Iniewski, Kris</creatorcontrib><creatorcontrib>Cunningham, Ian A.</creatorcontrib><title>Frequency‐dependent signal and noise in spectroscopic x‐ray imaging</title><title>Medical physics (Lancaster)</title><addtitle>Med Phys</addtitle><description>Purpose
We present a new framework for theoretical analysis of the noise power spectrum (NPS) of photon‐counting x‐ray detectors, including simple photon‐counting detectors (SPCDs) and spectroscopic x‐ray detectors (SXDs), the latter of which use multiple energy thresholds to discriminate photon energies.
Methods
We show that the NPS of SPCDs and SXDs, including spatio‐energetic noise correlations, is determined by the joint probability density function (PDF) of deposited photon energies, which describes the probability of recording two photons of two different energies in two different elements following a single‐photon interaction. We present an analytic expression for this joint PDF and calculate the presampling and digital NPS of CdTe SPCDs and SXDs. We calibrate our charge sharing model using the energy response of a cadmium zinc telluride (CZT) spectroscopic x‐ray detector and compare theoretical results with Monte Carlo simulations.
Results
Our analysis shows that charge sharing increases pixel signal‐to‐noise ratio (SNR), but degrades the zero‐frequency signal‐to‐noise performance of SPCDs and SXDs. In all cases considered, this degradation was greater than 10%. Comparing the presampling NPS with the sampled NPS showed that degradation in zero‐frequency performance is due to zero‐frequency noise aliasing induced by charge sharing.
Conclusions
Noise performance, including spatial and energy correlations between elements and energy bins, are described by the joint PDF of deposited energies which provides a method of determining the photon‐counting NPS, including noise‐aliasing effects and spatio‐energetic effects in spectral imaging. Our approach enables separating noise due to x‐ray interactions from that associated with sampling, consistent with cascaded systems analysis of energy‐integrating systems. Our methods can be incorporated into task‐based assessment of image quality for the design and optimization of spectroscopic x‐ray detectors.</description><subject>Cadmium Compounds</subject><subject>detective quantum efficiency</subject><subject>DIAGNOSTIC IMAGING (IONIZING AND NON‐IONIZING)</subject><subject>dual-energy imaging</subject><subject>noise power spectrum</subject><subject>photon-counting</subject><subject>Photons</subject><subject>Quantum Dots</subject><subject>spectroscopic x-ray imaging</subject><subject>Tellurium</subject><subject>X-Rays</subject><issn>0094-2405</issn><issn>2473-4209</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>24P</sourceid><sourceid>EIF</sourceid><recordid>eNp1kEFOwzAQRS0EoqUgcQKUJZuUsePEyQYJVbQgFcEC1pbrTIpR4oS4BbLjCJyRk2BoKbBgZY389ObPJ-SQwpACsJOqGVJOE9gifcZFFHIG2TbpA2Q8ZBziHtlz7gEAkiiGXdKLGIuymIo-mYxbfFyi1d3761uODdoc7SJwZm5VGSibB7Y2DgNjA9egXrS103VjdPDi-VZ1ganU3Nj5PtkpVOnwYP0OyN34_HZ0EU6vJ5ejs2mouU8azjgVGrDAVCCqWGkoCgWKiUQhT3WaAitA6zyLmEbBWYx-TIBSSCGjmkUDcrryNstZhbn2YVtVyqb1OdpO1srIvz_W3Mt5_SQFzxLBMi84Xgva2h_uFrIyTmNZKov10kkWpbGAVDD-g2p_tWux2KyhID97l1Ujv3r36NHvWBvwu2gPhCvg2ZTY_SuSVzcr4QcWD48B</recordid><startdate>202007</startdate><enddate>202007</enddate><creator>Tanguay, Jesse</creator><creator>Kim, Jinwoo</creator><creator>Kim, Ho Kyung</creator><creator>Iniewski, Kris</creator><creator>Cunningham, Ian A.</creator><general>John Wiley and Sons Inc</general><scope>24P</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>202007</creationdate><title>Frequency‐dependent signal and noise in spectroscopic x‐ray imaging</title><author>Tanguay, Jesse ; Kim, Jinwoo ; Kim, Ho Kyung ; Iniewski, Kris ; Cunningham, Ian A.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4100-b417c0efe87eea5ac0ffa0a276ae48c8802f0ccd932ce7425ef0c601108091c23</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Cadmium Compounds</topic><topic>detective quantum efficiency</topic><topic>DIAGNOSTIC IMAGING (IONIZING AND NON‐IONIZING)</topic><topic>dual-energy imaging</topic><topic>noise power spectrum</topic><topic>photon-counting</topic><topic>Photons</topic><topic>Quantum Dots</topic><topic>spectroscopic x-ray imaging</topic><topic>Tellurium</topic><topic>X-Rays</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Tanguay, Jesse</creatorcontrib><creatorcontrib>Kim, Jinwoo</creatorcontrib><creatorcontrib>Kim, Ho Kyung</creatorcontrib><creatorcontrib>Iniewski, Kris</creatorcontrib><creatorcontrib>Cunningham, Ian A.</creatorcontrib><collection>Wiley Online Library Open Access</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Medical physics (Lancaster)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Tanguay, Jesse</au><au>Kim, Jinwoo</au><au>Kim, Ho Kyung</au><au>Iniewski, Kris</au><au>Cunningham, Ian A.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Frequency‐dependent signal and noise in spectroscopic x‐ray imaging</atitle><jtitle>Medical physics (Lancaster)</jtitle><addtitle>Med Phys</addtitle><date>2020-07</date><risdate>2020</risdate><volume>47</volume><issue>7</issue><spage>2881</spage><epage>2901</epage><pages>2881-2901</pages><issn>0094-2405</issn><eissn>2473-4209</eissn><abstract>Purpose
We present a new framework for theoretical analysis of the noise power spectrum (NPS) of photon‐counting x‐ray detectors, including simple photon‐counting detectors (SPCDs) and spectroscopic x‐ray detectors (SXDs), the latter of which use multiple energy thresholds to discriminate photon energies.
Methods
We show that the NPS of SPCDs and SXDs, including spatio‐energetic noise correlations, is determined by the joint probability density function (PDF) of deposited photon energies, which describes the probability of recording two photons of two different energies in two different elements following a single‐photon interaction. We present an analytic expression for this joint PDF and calculate the presampling and digital NPS of CdTe SPCDs and SXDs. We calibrate our charge sharing model using the energy response of a cadmium zinc telluride (CZT) spectroscopic x‐ray detector and compare theoretical results with Monte Carlo simulations.
Results
Our analysis shows that charge sharing increases pixel signal‐to‐noise ratio (SNR), but degrades the zero‐frequency signal‐to‐noise performance of SPCDs and SXDs. In all cases considered, this degradation was greater than 10%. Comparing the presampling NPS with the sampled NPS showed that degradation in zero‐frequency performance is due to zero‐frequency noise aliasing induced by charge sharing.
Conclusions
Noise performance, including spatial and energy correlations between elements and energy bins, are described by the joint PDF of deposited energies which provides a method of determining the photon‐counting NPS, including noise‐aliasing effects and spatio‐energetic effects in spectral imaging. Our approach enables separating noise due to x‐ray interactions from that associated with sampling, consistent with cascaded systems analysis of energy‐integrating systems. Our methods can be incorporated into task‐based assessment of image quality for the design and optimization of spectroscopic x‐ray detectors.</abstract><cop>United States</cop><pub>John Wiley and Sons Inc</pub><pmid>32239517</pmid><doi>10.1002/mp.14160</doi><tpages>23</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Cadmium Compounds detective quantum efficiency DIAGNOSTIC IMAGING (IONIZING AND NON‐IONIZING) dual-energy imaging noise power spectrum photon-counting Photons Quantum Dots spectroscopic x-ray imaging Tellurium X-Rays |
title | Frequency‐dependent signal and noise in spectroscopic x‐ray imaging |
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