Chemical simulation of hypoxia in donor cells improves development of somatic cell nuclear transfer‐derived embryos and increases abundance of transcripts related to glycolysis

To improve efficiency of somatic cell nuclear transfer (SCNT), it is necessary to modify differentiated donor cells to become more amendable for reprogramming by the oocyte cytoplasm. A key feature that distinguishes somatic/differentiated cells from embryonic/undifferentiated cells is cellular meta...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Molecular reproduction and development 2020-07, Vol.87 (7), p.763-772
Hauptverfasser:	Cecil, Raissa F., Chen, Paula R., Benne, Joshua A., Hord, Taylor K., Spate, Lee D., Samuel, Melissa S., Prather, Randall S.
Format:	Artikel
Sprache:	eng
Schlagworte:	cellular reprogramming hypoxia inducible factor metabolism porcine somatic cell nuclear transfer
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!