Janus Kinase Inhibition in the Aicardi-Goutières Syndrome
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Veröffentlicht in: | The New England journal of medicine 2020-09, Vol.383 (10), p.986-989 |
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creator | Vanderver, Adeline Adang, Laura Gavazzi, Francesco McDonald, Katherine Helman, Guy Frank, David B Jaffe, Nicole Yum, Sabrina W Collins, Abigail Keller, Stephanie R Lebon, Pierre Meritet, Jean-François Rhee, Jullie Takanohashi, Asako Armangue, Thais Ulrick, Nicole Sherbini, Omar Koh, Jamie Peer, Kyle Besnier, Constance Scher, Carly Boyle, Katherine Dubbs, Holly Kramer-Golinkoff, Julia Pizzino, Amy Woidill, Sarah Shults, Justine |
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doi_str_mv | 10.1056/nejmc2001362 |
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drug therapy ; Azetidines - adverse effects ; Azetidines - therapeutic use ; Biomarkers ; Child ; Child Development - drug effects ; Child, Preschool ; Dose-Response Relationship, Drug ; Female ; Gene Expression - drug effects ; Humans ; Infant ; Interferons - genetics ; Interferons - metabolism ; Janus Kinase Inhibitors - adverse effects ; Janus Kinase Inhibitors - therapeutic use ; Least-Squares Analysis ; Male ; Nervous System Malformations - drug therapy ; Sulfonamides - adverse effects ; Sulfonamides - therapeutic use ; Young Adult</subject><ispartof>The New England journal of medicine, 2020-09, Vol.383 (10), p.986-989</ispartof><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3652-1732c5b5a312a7c43bc08da83a36608a6452fd17c24459b132f86ee005a02ece3</citedby><cites>FETCH-LOGICAL-c3652-1732c5b5a312a7c43bc08da83a36608a6452fd17c24459b132f86ee005a02ece3</cites><orcidid>0000-0002-8454-1116</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,314,780,784,885,2759,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/32877590$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Vanderver, Adeline</creatorcontrib><creatorcontrib>Adang, Laura</creatorcontrib><creatorcontrib>Gavazzi, Francesco</creatorcontrib><creatorcontrib>McDonald, Katherine</creatorcontrib><creatorcontrib>Helman, Guy</creatorcontrib><creatorcontrib>Frank, David B</creatorcontrib><creatorcontrib>Jaffe, Nicole</creatorcontrib><creatorcontrib>Yum, Sabrina W</creatorcontrib><creatorcontrib>Collins, Abigail</creatorcontrib><creatorcontrib>Keller, Stephanie R</creatorcontrib><creatorcontrib>Lebon, Pierre</creatorcontrib><creatorcontrib>Meritet, Jean-François</creatorcontrib><creatorcontrib>Rhee, Jullie</creatorcontrib><creatorcontrib>Takanohashi, Asako</creatorcontrib><creatorcontrib>Armangue, Thais</creatorcontrib><creatorcontrib>Ulrick, Nicole</creatorcontrib><creatorcontrib>Sherbini, Omar</creatorcontrib><creatorcontrib>Koh, Jamie</creatorcontrib><creatorcontrib>Peer, Kyle</creatorcontrib><creatorcontrib>Besnier, Constance</creatorcontrib><creatorcontrib>Scher, Carly</creatorcontrib><creatorcontrib>Boyle, Katherine</creatorcontrib><creatorcontrib>Dubbs, Holly</creatorcontrib><creatorcontrib>Kramer-Golinkoff, Julia</creatorcontrib><creatorcontrib>Pizzino, Amy</creatorcontrib><creatorcontrib>Woidill, Sarah</creatorcontrib><creatorcontrib>Shults, Justine</creatorcontrib><title>Janus Kinase Inhibition in the Aicardi-Goutières Syndrome</title><title>The New England journal of medicine</title><addtitle>N Engl J Med</addtitle><subject>Adolescent</subject><subject>Age of Onset</subject><subject>Autoimmune Diseases of the Nervous System - drug therapy</subject><subject>Azetidines - adverse effects</subject><subject>Azetidines - therapeutic use</subject><subject>Biomarkers</subject><subject>Child</subject><subject>Child Development - drug effects</subject><subject>Child, Preschool</subject><subject>Dose-Response Relationship, Drug</subject><subject>Female</subject><subject>Gene Expression - drug effects</subject><subject>Humans</subject><subject>Infant</subject><subject>Interferons - genetics</subject><subject>Interferons - metabolism</subject><subject>Janus Kinase Inhibitors - adverse effects</subject><subject>Janus Kinase Inhibitors - therapeutic use</subject><subject>Least-Squares Analysis</subject><subject>Male</subject><subject>Nervous System Malformations - drug therapy</subject><subject>Sulfonamides - adverse effects</subject><subject>Sulfonamides - therapeutic use</subject><subject>Young Adult</subject><issn>0028-4793</issn><issn>1533-4406</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpVkM1OwkAURidGI4juXJs-gNU7_60LE0IQQdSFup5Mp1MZQqdkppjwRr6HLyYGIXo3d3G_79zkIHSO4QoDF9fezmtDADAV5AB1Mac0ZQzEIeoCkCxlMqcddBLjHDaDWX6MOpRkUvIcuuhmov0qJg_O62iTsZ-5wrWu8YnzSTuzSd8ZHUqXjppV674-g43Jy9qXoantKTqq9CLas9_dQ293w9fBfTp9Ho0H_WlqqOAkxZISwwuuKSZaGkYLA1mpM6qpEJBpwTipSiwNYYznBaakyoS1AFwDscbSHrrdcperoralsb4NeqGWwdU6rFWjnfp_8W6m3psPJVnOGYYN4HILMKGJMdhq38Wgfhyqp-HkcedwE7_4-28f3kmj3_EWbbQ</recordid><startdate>20200903</startdate><enddate>20200903</enddate><creator>Vanderver, Adeline</creator><creator>Adang, Laura</creator><creator>Gavazzi, Francesco</creator><creator>McDonald, Katherine</creator><creator>Helman, Guy</creator><creator>Frank, David B</creator><creator>Jaffe, Nicole</creator><creator>Yum, Sabrina W</creator><creator>Collins, Abigail</creator><creator>Keller, Stephanie R</creator><creator>Lebon, Pierre</creator><creator>Meritet, Jean-François</creator><creator>Rhee, Jullie</creator><creator>Takanohashi, Asako</creator><creator>Armangue, Thais</creator><creator>Ulrick, Nicole</creator><creator>Sherbini, Omar</creator><creator>Koh, Jamie</creator><creator>Peer, Kyle</creator><creator>Besnier, Constance</creator><creator>Scher, Carly</creator><creator>Boyle, Katherine</creator><creator>Dubbs, Holly</creator><creator>Kramer-Golinkoff, Julia</creator><creator>Pizzino, Amy</creator><creator>Woidill, Sarah</creator><creator>Shults, Justine</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0002-8454-1116</orcidid></search><sort><creationdate>20200903</creationdate><title>Janus Kinase Inhibition in the Aicardi-Goutières Syndrome</title><author>Vanderver, Adeline ; Adang, Laura ; Gavazzi, Francesco ; McDonald, Katherine ; Helman, Guy ; Frank, David B ; Jaffe, Nicole ; Yum, Sabrina W ; Collins, Abigail ; Keller, Stephanie R ; Lebon, Pierre ; Meritet, Jean-François ; Rhee, Jullie ; Takanohashi, Asako ; Armangue, Thais ; Ulrick, Nicole ; Sherbini, Omar ; Koh, Jamie ; Peer, Kyle ; Besnier, Constance ; Scher, Carly ; Boyle, Katherine ; Dubbs, Holly ; Kramer-Golinkoff, Julia ; Pizzino, Amy ; Woidill, Sarah ; Shults, Justine</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3652-1732c5b5a312a7c43bc08da83a36608a6452fd17c24459b132f86ee005a02ece3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Adolescent</topic><topic>Age of Onset</topic><topic>Autoimmune Diseases of the Nervous System - 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subjects | Adolescent Age of Onset Autoimmune Diseases of the Nervous System - drug therapy Azetidines - adverse effects Azetidines - therapeutic use Biomarkers Child Child Development - drug effects Child, Preschool Dose-Response Relationship, Drug Female Gene Expression - drug effects Humans Infant Interferons - genetics Interferons - metabolism Janus Kinase Inhibitors - adverse effects Janus Kinase Inhibitors - therapeutic use Least-Squares Analysis Male Nervous System Malformations - drug therapy Sulfonamides - adverse effects Sulfonamides - therapeutic use Young Adult |
title | Janus Kinase Inhibition in the Aicardi-Goutières Syndrome |
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