Anti-Chikungunya Virus Monoclonal Antibody That Inhibits Viral Fusion and Release

Chikungunya fever, a mosquito-borne disease manifested by fever, rash, myalgia, and arthralgia, is caused by chikungunya virus (CHIKV), which belongs to the genus of the family Anti-CHIKV IgG from convalescent patients is known to directly neutralize CHIKV, and the state of immunity lasts throughout...

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Veröffentlicht in:	Journal of virology 2020-09, Vol.94 (19)
Hauptverfasser:	Tumkosit, Uranan, Siripanyaphinyo, Uamporn, Takeda, Naokazu, Tsuji, Motonori, Maeda, Yusuke, Ruchusatsawat, Kriangsak, Shioda, Tatsuo, Mizushima, Hiroto, Chetanachan, Prukswan, Wongjaroen, Pattara, Matsuura, Yoshiharu, Tatsumi, Masashi, Tanaka, Atsushi
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies, Monoclonal - immunology Antibodies, Neutralizing - immunology Antibodies, Viral - chemistry Antibodies, Viral - immunology Antibodies, Viral - pharmacology Chikungunya Fever - immunology Chikungunya virus - genetics Chikungunya virus - immunology Chikungunya virus - physiology Chlorocebus aethiops Epitopes - immunology Female Membrane Fusion - immunology Mice Mice, Inbred BALB C Molecular Docking Simulation Protein Interaction Domains and Motifs Vaccines and Antiviral Agents Vero Cells Viral Envelope Proteins - chemistry Viral Envelope Proteins - drug effects Viral Envelope Proteins - genetics Viral Envelope Proteins - immunology Viral Fusion Proteins - chemistry Viral Fusion Proteins - immunology Virus Internalization - drug effects Virus Release - drug effects Virus Release - immunology
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