Mortality Risk Profiling of Staphylococcus aureus Bacteremia by Multi-omic Serum Analysis Reveals Early Predictive and Pathogenic Molecular Signatures

Staphylococcus aureus bacteremia (SaB) causes significant disease in humans, carrying mortality rates of ~25%. The ability to rapidly predict SaB patient responses and guide personalized treatment regimens could reduce mortality. Here, we present a resource of SaB prognostic biomarkers. Integrating...

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Veröffentlicht in:Cell 2020-09, Vol.182 (5), p.1311-1327.e14
Hauptverfasser: Wozniak, Jacob M., Mills, Robert H., Olson, Joshua, Caldera, JR, Sepich-Poore, Gregory D., Carrillo-Terrazas, Marvic, Tsai, Chih-Ming, Vargas, Fernando, Knight, Rob, Dorrestein, Pieter C., Liu, George Y., Nizet, Victor, Sakoulas, George, Rose, Warren, Gonzalez, David J.
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Sprache:eng
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