Coronavirus Disease 2019 (COVID-19): A Haematologist’s Perspective
Coronavirus disease 2019 (COVID-19) is affecting millions of patients worldwide. It is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which belongs to the family Coronaviridae, with 80% genomic similarities to SARS-CoV. Lymphopenia was commonly seen in infected patients...
Gespeichert in:
| Veröffentlicht in: | Acta haematologica 2021-01, Vol.144 (1), p.10-23 |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 23 |
|---|---|
| container_issue | 1 |
| container_start_page | 10 |
| container_title | Acta haematologica |
| container_volume | 144 |
| creator | Cheung, Carmen Ka Man Law, Man Fai Lui, Grace Chung Yan Wong, Sunny Hei Wong, Raymond Siu Ming |
| description | Coronavirus disease 2019 (COVID-19) is affecting millions of patients worldwide. It is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which belongs to the family Coronaviridae, with 80% genomic similarities to SARS-CoV. Lymphopenia was commonly seen in infected patients and has a correlation to disease severity. Thrombocytopenia, coagulation abnormalities, and disseminated intravascular coagulation were observed in COVID-19 patients, especially those with critical illness and non-survivors. This pandemic has caused disruption in communities and hospital services, as well as straining blood product supply, affecting chemotherapy treatment and haematopoietic stem cell transplantation schedule. In this article, we review the haematological manifestations of the disease and its implication on the management of patients with haematological disorders. |
| doi_str_mv | 10.1159/000510178 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7490512</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2428554948</sourcerecordid><originalsourceid>FETCH-LOGICAL-c452t-1aa725acb50b2a645962c60667a77b47060dcefa6b0c6cc45e9e3aa84a72664b3</originalsourceid><addsrcrecordid>eNptkM9KAzEQxoMoWqsH7yILXuphNcnmz8aDUFq1hYIe1GuYjWld3TY12Ra8-Rq-nk9ipHVR8DTMzO_7ZvgQOiD4lBCuzjDGnGAi8w3UIoySVAlBN1ErzknKpaI7aDeE59hRmalttJNRSYnieQv1e867GSxLvwhJvwwWgk0oJirp9G4ehv2UqJPzpJsMwE6hdpWblKH-fP8Iya31YW5NXS7tHtoaQxXs_rq20f3V5V1vkI5uroe97ig1jNM6JQCScjAFxwUFwbgS1AgshAQpCyaxwI_GjkEU2AgTNVbZDCBnUSYEK7I2ulj5zhfF1EZ2Vnuo9NyXU_Bv2kGp_25m5ZOeuKWWTMWEaDTorA28e13YUOtpGYytKphZtwiaMppzzhTLI3qyQo13IXg7bs4QrL9T103qkT36_VdD_sQcgcMV8AJ-Yn0DNPrjf9fdQXdF6PnjOPsC2EqQow</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2428554948</pqid></control><display><type>article</type><title>Coronavirus Disease 2019 (COVID-19): A Haematologist’s Perspective</title><source>Karger电子期刊和电子书数据库</source><source>MEDLINE</source><creator>Cheung, Carmen Ka Man ; Law, Man Fai ; Lui, Grace Chung Yan ; Wong, Sunny Hei ; Wong, Raymond Siu Ming</creator><creatorcontrib>Cheung, Carmen Ka Man ; Law, Man Fai ; Lui, Grace Chung Yan ; Wong, Sunny Hei ; Wong, Raymond Siu Ming</creatorcontrib><description>Coronavirus disease 2019 (COVID-19) is affecting millions of patients worldwide. It is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which belongs to the family Coronaviridae, with 80% genomic similarities to SARS-CoV. Lymphopenia was commonly seen in infected patients and has a correlation to disease severity. Thrombocytopenia, coagulation abnormalities, and disseminated intravascular coagulation were observed in COVID-19 patients, especially those with critical illness and non-survivors. This pandemic has caused disruption in communities and hospital services, as well as straining blood product supply, affecting chemotherapy treatment and haematopoietic stem cell transplantation schedule. In this article, we review the haematological manifestations of the disease and its implication on the management of patients with haematological disorders.</description><identifier>ISSN: 0001-5792</identifier><identifier>EISSN: 1421-9662</identifier><identifier>DOI: 10.1159/000510178</identifier><identifier>PMID: 32721958</identifier><language>eng</language><publisher>Basel, Switzerland: S. Karger AG</publisher><subject>COVID-19 - blood ; COVID-19 - mortality ; COVID-19 - therapy ; Disseminated Intravascular Coagulation - blood ; Disseminated Intravascular Coagulation - mortality ; Disseminated Intravascular Coagulation - therapy ; Disseminated Intravascular Coagulation - virology ; Hematopoietic Stem Cell Transplantation ; Humans ; Lymphopenia - blood ; Lymphopenia - mortality ; Lymphopenia - therapy ; Lymphopenia - virology ; Pandemics ; Review ; SARS-CoV-2 - metabolism ; Thrombocytopenia - blood ; Thrombocytopenia - mortality ; Thrombocytopenia - therapy ; Thrombocytopenia - virology</subject><ispartof>Acta haematologica, 2021-01, Vol.144 (1), p.10-23</ispartof><rights>2020 S. Karger AG, Basel</rights><rights>2020 S. Karger AG, Basel.</rights><rights>Copyright © 2020 by S. Karger AG, Basel 2020</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c452t-1aa725acb50b2a645962c60667a77b47060dcefa6b0c6cc45e9e3aa84a72664b3</citedby><cites>FETCH-LOGICAL-c452t-1aa725acb50b2a645962c60667a77b47060dcefa6b0c6cc45e9e3aa84a72664b3</cites><orcidid>0000-0002-9011-4268</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,314,776,780,881,2423,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/32721958$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Cheung, Carmen Ka Man</creatorcontrib><creatorcontrib>Law, Man Fai</creatorcontrib><creatorcontrib>Lui, Grace Chung Yan</creatorcontrib><creatorcontrib>Wong, Sunny Hei</creatorcontrib><creatorcontrib>Wong, Raymond Siu Ming</creatorcontrib><title>Coronavirus Disease 2019 (COVID-19): A Haematologist’s Perspective</title><title>Acta haematologica</title><addtitle>Acta Haematol</addtitle><description>Coronavirus disease 2019 (COVID-19) is affecting millions of patients worldwide. It is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which belongs to the family Coronaviridae, with 80% genomic similarities to SARS-CoV. Lymphopenia was commonly seen in infected patients and has a correlation to disease severity. Thrombocytopenia, coagulation abnormalities, and disseminated intravascular coagulation were observed in COVID-19 patients, especially those with critical illness and non-survivors. This pandemic has caused disruption in communities and hospital services, as well as straining blood product supply, affecting chemotherapy treatment and haematopoietic stem cell transplantation schedule. In this article, we review the haematological manifestations of the disease and its implication on the management of patients with haematological disorders.</description><subject>COVID-19 - blood</subject><subject>COVID-19 - mortality</subject><subject>COVID-19 - therapy</subject><subject>Disseminated Intravascular Coagulation - blood</subject><subject>Disseminated Intravascular Coagulation - mortality</subject><subject>Disseminated Intravascular Coagulation - therapy</subject><subject>Disseminated Intravascular Coagulation - virology</subject><subject>Hematopoietic Stem Cell Transplantation</subject><subject>Humans</subject><subject>Lymphopenia - blood</subject><subject>Lymphopenia - mortality</subject><subject>Lymphopenia - therapy</subject><subject>Lymphopenia - virology</subject><subject>Pandemics</subject><subject>Review</subject><subject>SARS-CoV-2 - metabolism</subject><subject>Thrombocytopenia - blood</subject><subject>Thrombocytopenia - mortality</subject><subject>Thrombocytopenia - therapy</subject><subject>Thrombocytopenia - virology</subject><issn>0001-5792</issn><issn>1421-9662</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNptkM9KAzEQxoMoWqsH7yILXuphNcnmz8aDUFq1hYIe1GuYjWld3TY12Ra8-Rq-nk9ipHVR8DTMzO_7ZvgQOiD4lBCuzjDGnGAi8w3UIoySVAlBN1ErzknKpaI7aDeE59hRmalttJNRSYnieQv1e867GSxLvwhJvwwWgk0oJirp9G4ehv2UqJPzpJsMwE6hdpWblKH-fP8Iya31YW5NXS7tHtoaQxXs_rq20f3V5V1vkI5uroe97ig1jNM6JQCScjAFxwUFwbgS1AgshAQpCyaxwI_GjkEU2AgTNVbZDCBnUSYEK7I2ulj5zhfF1EZ2Vnuo9NyXU_Bv2kGp_25m5ZOeuKWWTMWEaDTorA28e13YUOtpGYytKphZtwiaMppzzhTLI3qyQo13IXg7bs4QrL9T103qkT36_VdD_sQcgcMV8AJ-Yn0DNPrjf9fdQXdF6PnjOPsC2EqQow</recordid><startdate>20210101</startdate><enddate>20210101</enddate><creator>Cheung, Carmen Ka Man</creator><creator>Law, Man Fai</creator><creator>Lui, Grace Chung Yan</creator><creator>Wong, Sunny Hei</creator><creator>Wong, Raymond Siu Ming</creator><general>S. Karger AG</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0002-9011-4268</orcidid></search><sort><creationdate>20210101</creationdate><title>Coronavirus Disease 2019 (COVID-19): A Haematologist’s Perspective</title><author>Cheung, Carmen Ka Man ; Law, Man Fai ; Lui, Grace Chung Yan ; Wong, Sunny Hei ; Wong, Raymond Siu Ming</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c452t-1aa725acb50b2a645962c60667a77b47060dcefa6b0c6cc45e9e3aa84a72664b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>COVID-19 - blood</topic><topic>COVID-19 - mortality</topic><topic>COVID-19 - therapy</topic><topic>Disseminated Intravascular Coagulation - blood</topic><topic>Disseminated Intravascular Coagulation - mortality</topic><topic>Disseminated Intravascular Coagulation - therapy</topic><topic>Disseminated Intravascular Coagulation - virology</topic><topic>Hematopoietic Stem Cell Transplantation</topic><topic>Humans</topic><topic>Lymphopenia - blood</topic><topic>Lymphopenia - mortality</topic><topic>Lymphopenia - therapy</topic><topic>Lymphopenia - virology</topic><topic>Pandemics</topic><topic>Review</topic><topic>SARS-CoV-2 - metabolism</topic><topic>Thrombocytopenia - blood</topic><topic>Thrombocytopenia - mortality</topic><topic>Thrombocytopenia - therapy</topic><topic>Thrombocytopenia - virology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Cheung, Carmen Ka Man</creatorcontrib><creatorcontrib>Law, Man Fai</creatorcontrib><creatorcontrib>Lui, Grace Chung Yan</creatorcontrib><creatorcontrib>Wong, Sunny Hei</creatorcontrib><creatorcontrib>Wong, Raymond Siu Ming</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Acta haematologica</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Cheung, Carmen Ka Man</au><au>Law, Man Fai</au><au>Lui, Grace Chung Yan</au><au>Wong, Sunny Hei</au><au>Wong, Raymond Siu Ming</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Coronavirus Disease 2019 (COVID-19): A Haematologist’s Perspective</atitle><jtitle>Acta haematologica</jtitle><addtitle>Acta Haematol</addtitle><date>2021-01-01</date><risdate>2021</risdate><volume>144</volume><issue>1</issue><spage>10</spage><epage>23</epage><pages>10-23</pages><issn>0001-5792</issn><eissn>1421-9662</eissn><abstract>Coronavirus disease 2019 (COVID-19) is affecting millions of patients worldwide. It is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which belongs to the family Coronaviridae, with 80% genomic similarities to SARS-CoV. Lymphopenia was commonly seen in infected patients and has a correlation to disease severity. Thrombocytopenia, coagulation abnormalities, and disseminated intravascular coagulation were observed in COVID-19 patients, especially those with critical illness and non-survivors. This pandemic has caused disruption in communities and hospital services, as well as straining blood product supply, affecting chemotherapy treatment and haematopoietic stem cell transplantation schedule. In this article, we review the haematological manifestations of the disease and its implication on the management of patients with haematological disorders.</abstract><cop>Basel, Switzerland</cop><pub>S. Karger AG</pub><pmid>32721958</pmid><doi>10.1159/000510178</doi><tpages>14</tpages><orcidid>https://orcid.org/0000-0002-9011-4268</orcidid><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0001-5792 |
| ispartof | Acta haematologica, 2021-01, Vol.144 (1), p.10-23 |
| issn | 0001-5792 1421-9662 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7490512 |
| source | Karger电子期刊和电子书数据库; MEDLINE |
| subjects | COVID-19 - blood COVID-19 - mortality COVID-19 - therapy Disseminated Intravascular Coagulation - blood Disseminated Intravascular Coagulation - mortality Disseminated Intravascular Coagulation - therapy Disseminated Intravascular Coagulation - virology Hematopoietic Stem Cell Transplantation Humans Lymphopenia - blood Lymphopenia - mortality Lymphopenia - therapy Lymphopenia - virology Pandemics Review SARS-CoV-2 - metabolism Thrombocytopenia - blood Thrombocytopenia - mortality Thrombocytopenia - therapy Thrombocytopenia - virology |
| title | Coronavirus Disease 2019 (COVID-19): A Haematologist’s Perspective |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-12T07%3A11%3A32IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Coronavirus%20Disease%202019%20(COVID-19):%20A%20Haematologist%E2%80%99s%20Perspective&rft.jtitle=Acta%20haematologica&rft.au=Cheung,%20Carmen%C2%A0Ka%C2%A0Man&rft.date=2021-01-01&rft.volume=144&rft.issue=1&rft.spage=10&rft.epage=23&rft.pages=10-23&rft.issn=0001-5792&rft.eissn=1421-9662&rft_id=info:doi/10.1159/000510178&rft_dat=%3Cproquest_pubme%3E2428554948%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2428554948&rft_id=info:pmid/32721958&rfr_iscdi=true |