Pannexin 1 channels in renin-expressing cells influence renin secretion and blood pressure homeostasis

Kidney function and blood pressure homeostasis are regulated by purinergic signaling mechanisms. These autocrine/paracrine signaling pathways are initiated by the release of cellular ATP, which influences kidney hemodynamics and steady-state renin secretion from juxtaglomerular cells. However, the m...

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Veröffentlicht in:	Kidney international 2020-09, Vol.98 (3), p.630-644
Hauptverfasser:	DeLalio, Leon J., Masati, Ester, Mendu, Suresh, Ruddiman, Claire A., Yang, Yang, Johnstone, Scott R., Milstein, Jenna A., Keller, T.C. Stevenson, Weaver, Rachel B., Guagliardo, Nick A., Best, Angela K., Ravichandran, Kodi S., Bayliss, Douglas A., Sequeira-Lopez, Maria Luisa S., Sonkusare, Swapnil N., Shu, Xiaohong H., Desai, Bimal, Barrett, Paula Q., Le, Thu H., Gomez, R. Ariel, Isakson, Brant E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Triphosphate Animals Blood Pressure Connexins - genetics Female Homeostasis kidney Male Mice Mice, Knockout Nerve Tissue Proteins - genetics Pannexin 1 purinergic RAAS Renin
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