Predictive in silico binding algorithms reveal HLA specificities and autoallergen peptides associated with atopic dermatitis

Atopic dermatitis (AD) is a skin disease that results from a combination of skin barrier dysfunction and immune dysregulation. The immune dysregulation is often associated with IgE sensitivity. There is also evidence that autoallergens Hom s 1, 2, 3, and 4 play a role in AD; it is possible that pati...

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Veröffentlicht in:	Archives of Dermatological Research 2020-11, Vol.312 (9), p.647-656
Hauptverfasser:	Gong, Jan J., Margolis, David J., Monos, Dimitrios S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Algorithms Alleles Atopic dermatitis Dermatitis Dermatology Drb1 protein Eczema Epitopes Histocompatibility antigen HLA Immunoglobulin E Medicine Medicine & Public Health Original Paper Peptides Skin diseases
Online-Zugang:	Volltext
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