DNMT3A alterations associated with myeloid malignancies dictate differential responses to hypomethylating agents

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Veröffentlicht in:Leukemia research 2020-07, Vol.94, p.106372-106372, Article 106372
Hauptverfasser: Casellas Román, Heidi L., Venugopal, Kartika, Feng, Yang, Shabashvili, Daniil E., Posada, Luisa M., Li, Jianping, Guryanova, Olga A.
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container_title Leukemia research
container_volume 94
creator Casellas Román, Heidi L.
Venugopal, Kartika
Feng, Yang
Shabashvili, Daniil E.
Posada, Luisa M.
Li, Jianping
Guryanova, Olga A.
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doi_str_mv 10.1016/j.leukres.2020.106372
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source MEDLINE; ScienceDirect Journals (5 years ago - present)
subjects AML
Animals
DAC
Decitabine
Decitabine - pharmacology
DNA (Cytosine-5-)-Methyltransferases - genetics
DNA (Cytosine-5-)-Methyltransferases - metabolism
DNA hypomethylating agents (HMA)
DNA Methyltransferase 3A
DNMT3A
Leukemia, Myeloid, Acute - enzymology
Leukemia, Myeloid, Acute - genetics
Leukemia, Myeloid, Acute - pathology
MDS
Mice
Mice, Transgenic
Myelodysplastic Syndromes - drug therapy
Myelodysplastic Syndromes - enzymology
Myelodysplastic Syndromes - genetics
Myelodysplastic Syndromes - pathology
Neoplasm Proteins - genetics
Neoplasm Proteins - metabolism
title DNMT3A alterations associated with myeloid malignancies dictate differential responses to hypomethylating agents
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