Regulation of Energy Expenditure by Brainstem GABA Neurons

Homeostatic control of core body temperature is essential for survival. Temperature is sensed by specific neurons, in turn eliciting both behavioral (i.e., locomotion) and physiologic (i.e., thermogenesis, vasodilatation) responses. Here, we report that a population of GABAergic (Vgat-expressing) ne...

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Veröffentlicht in:	Cell 2019-07, Vol.178 (3), p.672-685.e12
Hauptverfasser:	Schneeberger, Marc, Parolari, Luca, Das Banerjee, Tania, Bhave, Varun, Wang, Putianqi, Patel, Bindiben, Topilko, Thomas, Wu, Zhuhao, Choi, Chan Hee J., Yu, Xiaofei, Pellegrino, Kyle, Engel, Esteban A., Cohen, Paul, Renier, Nicolas, Friedman, Jeffrey M., Nectow, Alexander R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipose Tissue, Brown - metabolism Adipose TissueBrown / metabolism Animals Brain Mapping Clozapine - analogs & derivatives Clozapine - pharmacology Dorsal Raphe Nucleus - metabolism Energy Metabolism GABAergic Neurons - metabolism Gene Expression - drug effects Genetic Vectors - genetics Genetic Vectors - metabolism Human health and pathology Life Sciences Mice Mice, Inbred C57BL Mice, Transgenic Optogenetics Temperature Thermogenesis
Online-Zugang:	Volltext
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