Efficacy and safety of thread embedding acupuncture on knee osteoarthritis: A randomized, controlled, pilot clinical trial
Although there are various therapeutic methods for the treatment of knee osteoarthritis, each has its advantages and shortcomings, and a definitive treatment method is yet to be determined. This pilot study is designed to obtain basic data for a further large-scale trial as well as provide informati...
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| Veröffentlicht in: | Medicine (Baltimore) 2020-09, Vol.99 (36), p.e21957-e21957 |
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| container_title | Medicine (Baltimore) |
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| creator | Jun, Purumea Han, Chang-Hyun Yang, Chang Sop Kim, Min Ji Kim, Jae Soo Lee, Cho In Lee, Jung Hee Park, Chung A Lee, Young Joon Lee, Hyun-Jong |
| description | Although there are various therapeutic methods for the treatment of knee osteoarthritis, each has its advantages and shortcomings, and a definitive treatment method is yet to be determined. This pilot study is designed to obtain basic data for a further large-scale trial as well as provide information about the feasibility of thread embedding acupuncture (TEA) with polydioxanone thread in knee osteoarthritis patients.
This study is a clinical trial to evaluate the efficacy and safety of TEA for knee osteoarthritis. Forty participants will be recruited at the hospital and after randomization into 2 groups of 20 (experimental and control); they will be treated for 6 weeks. The experimental group will receive TEA treatment 6 times (1 time/week) in 6 weeks on 14 defined knee areas, and the control group, acupuncture treatments 12 times (2 times/week) in 6 weeks on 9 defined acupuncture points. The visual analogue scale (VAS) will be used for the primary efficacy assessment and Short-form McGill Pain Questionnaire (SF-MPQ), Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) will be used for the secondary efficacy assessment. The follow-ups before clinical trial, 3 weeks after procedure, 6 weeks after procedure, and 4 weeks after the end of procedure will be done to compare the degree of pain with the control group, which received the acupuncture treatment.
The trial based on this study will provide clinical information on the efficacy and safety of TEA treatment on knee osteoarthritis.
KCT0004844. |
| doi_str_mv | 10.1097/MD.0000000000021957 |
| format | Article |
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This study is a clinical trial to evaluate the efficacy and safety of TEA for knee osteoarthritis. Forty participants will be recruited at the hospital and after randomization into 2 groups of 20 (experimental and control); they will be treated for 6 weeks. The experimental group will receive TEA treatment 6 times (1 time/week) in 6 weeks on 14 defined knee areas, and the control group, acupuncture treatments 12 times (2 times/week) in 6 weeks on 9 defined acupuncture points. The visual analogue scale (VAS) will be used for the primary efficacy assessment and Short-form McGill Pain Questionnaire (SF-MPQ), Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) will be used for the secondary efficacy assessment. The follow-ups before clinical trial, 3 weeks after procedure, 6 weeks after procedure, and 4 weeks after the end of procedure will be done to compare the degree of pain with the control group, which received the acupuncture treatment.
The trial based on this study will provide clinical information on the efficacy and safety of TEA treatment on knee osteoarthritis.
KCT0004844.</description><identifier>ISSN: 0025-7974</identifier><identifier>EISSN: 1536-5964</identifier><identifier>DOI: 10.1097/MD.0000000000021957</identifier><identifier>PMID: 32899030</identifier><language>eng</language><publisher>United States: Lippincott Williams & Wilkins</publisher><subject>Acupuncture Therapy - adverse effects ; Acupuncture Therapy - methods ; Humans ; Osteoarthritis, Knee - therapy ; Pain Measurement - methods ; Polydioxanone - therapeutic use ; Study Protocol Clinical Trial ; Visual Analog Scale</subject><ispartof>Medicine (Baltimore), 2020-09, Vol.99 (36), p.e21957-e21957</ispartof><rights>Copyright © 2020 the Author(s). Published by Wolters Kluwer Health, Inc. 2020</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c310t-b3ece3b0953161c6d5a602efb0b06fbc4f0d7589d0534214eead83e98c8beb263</cites><orcidid>0000-0003-0779-8433</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7478827/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7478827/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,724,777,781,861,882,27905,27906,53772,53774</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/32899030$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Jun, Purumea</creatorcontrib><creatorcontrib>Han, Chang-Hyun</creatorcontrib><creatorcontrib>Yang, Chang Sop</creatorcontrib><creatorcontrib>Kim, Min Ji</creatorcontrib><creatorcontrib>Kim, Jae Soo</creatorcontrib><creatorcontrib>Lee, Cho In</creatorcontrib><creatorcontrib>Lee, Jung Hee</creatorcontrib><creatorcontrib>Park, Chung A</creatorcontrib><creatorcontrib>Lee, Young Joon</creatorcontrib><creatorcontrib>Lee, Hyun-Jong</creatorcontrib><title>Efficacy and safety of thread embedding acupuncture on knee osteoarthritis: A randomized, controlled, pilot clinical trial</title><title>Medicine (Baltimore)</title><addtitle>Medicine (Baltimore)</addtitle><description>Although there are various therapeutic methods for the treatment of knee osteoarthritis, each has its advantages and shortcomings, and a definitive treatment method is yet to be determined. This pilot study is designed to obtain basic data for a further large-scale trial as well as provide information about the feasibility of thread embedding acupuncture (TEA) with polydioxanone thread in knee osteoarthritis patients.
This study is a clinical trial to evaluate the efficacy and safety of TEA for knee osteoarthritis. Forty participants will be recruited at the hospital and after randomization into 2 groups of 20 (experimental and control); they will be treated for 6 weeks. The experimental group will receive TEA treatment 6 times (1 time/week) in 6 weeks on 14 defined knee areas, and the control group, acupuncture treatments 12 times (2 times/week) in 6 weeks on 9 defined acupuncture points. The visual analogue scale (VAS) will be used for the primary efficacy assessment and Short-form McGill Pain Questionnaire (SF-MPQ), Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) will be used for the secondary efficacy assessment. The follow-ups before clinical trial, 3 weeks after procedure, 6 weeks after procedure, and 4 weeks after the end of procedure will be done to compare the degree of pain with the control group, which received the acupuncture treatment.
The trial based on this study will provide clinical information on the efficacy and safety of TEA treatment on knee osteoarthritis.
KCT0004844.</description><subject>Acupuncture Therapy - adverse effects</subject><subject>Acupuncture Therapy - methods</subject><subject>Humans</subject><subject>Osteoarthritis, Knee - therapy</subject><subject>Pain Measurement - methods</subject><subject>Polydioxanone - therapeutic use</subject><subject>Study Protocol Clinical Trial</subject><subject>Visual Analog Scale</subject><issn>0025-7974</issn><issn>1536-5964</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpdUV1PFTEQbYxErugvMDF99MHFdttud30wIYAfCYQXfG7a7hSq3fbadkkuv94SEJV5mcnMmXNOchB6Q8khJZP8cH5ySP5WTychn6ENFWzoxDTw52jTtqKTk-T76GUpPwihTPb8Bdpn_ThNhJENuj11zlttd1jHGRftoO5wcrheZ9AzhsXAPPt4hbVdt2u0dc2AU8Q_I7ReKiSdG9ZXXz7iI5wbS1r8LczvsU2x5hTC3bz1IVVsg49NLOCavQ6v0J7TocDrh36Avn8-vTz-2p1dfPl2fHTWWUZJ7QwDC8yQSTA6UDvMQg-kB2eIIYMzljsySzFOMxGM95RD8z0ymEY7GjD9wA7Qp3ve7WoWmC00WzqobfaLzjuVtFf_X6K_VlfpRkkux7GXjeDdA0FOv1YoVS2-WAhBR0hrUT3ntJcjkaJB2T3U5lRKBvcoQ4m6S02dn6inqbWvt_86fPz5ExP7DeT4lgQ</recordid><startdate>20200904</startdate><enddate>20200904</enddate><creator>Jun, Purumea</creator><creator>Han, Chang-Hyun</creator><creator>Yang, Chang Sop</creator><creator>Kim, Min Ji</creator><creator>Kim, Jae Soo</creator><creator>Lee, Cho In</creator><creator>Lee, Jung Hee</creator><creator>Park, Chung A</creator><creator>Lee, Young Joon</creator><creator>Lee, Hyun-Jong</creator><general>Lippincott Williams & Wilkins</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0003-0779-8433</orcidid></search><sort><creationdate>20200904</creationdate><title>Efficacy and safety of thread embedding acupuncture on knee osteoarthritis: A randomized, controlled, pilot clinical trial</title><author>Jun, Purumea ; Han, Chang-Hyun ; Yang, Chang Sop ; Kim, Min Ji ; Kim, Jae Soo ; Lee, Cho In ; Lee, Jung Hee ; Park, Chung A ; Lee, Young Joon ; Lee, Hyun-Jong</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c310t-b3ece3b0953161c6d5a602efb0b06fbc4f0d7589d0534214eead83e98c8beb263</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Acupuncture Therapy - adverse effects</topic><topic>Acupuncture Therapy - methods</topic><topic>Humans</topic><topic>Osteoarthritis, Knee - therapy</topic><topic>Pain Measurement - methods</topic><topic>Polydioxanone - therapeutic use</topic><topic>Study Protocol Clinical Trial</topic><topic>Visual Analog Scale</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Jun, Purumea</creatorcontrib><creatorcontrib>Han, Chang-Hyun</creatorcontrib><creatorcontrib>Yang, Chang Sop</creatorcontrib><creatorcontrib>Kim, Min Ji</creatorcontrib><creatorcontrib>Kim, Jae Soo</creatorcontrib><creatorcontrib>Lee, Cho In</creatorcontrib><creatorcontrib>Lee, Jung Hee</creatorcontrib><creatorcontrib>Park, Chung A</creatorcontrib><creatorcontrib>Lee, Young Joon</creatorcontrib><creatorcontrib>Lee, Hyun-Jong</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Medicine (Baltimore)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Jun, Purumea</au><au>Han, Chang-Hyun</au><au>Yang, Chang Sop</au><au>Kim, Min Ji</au><au>Kim, Jae Soo</au><au>Lee, Cho In</au><au>Lee, Jung Hee</au><au>Park, Chung A</au><au>Lee, Young Joon</au><au>Lee, Hyun-Jong</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Efficacy and safety of thread embedding acupuncture on knee osteoarthritis: A randomized, controlled, pilot clinical trial</atitle><jtitle>Medicine (Baltimore)</jtitle><addtitle>Medicine (Baltimore)</addtitle><date>2020-09-04</date><risdate>2020</risdate><volume>99</volume><issue>36</issue><spage>e21957</spage><epage>e21957</epage><pages>e21957-e21957</pages><issn>0025-7974</issn><eissn>1536-5964</eissn><abstract>Although there are various therapeutic methods for the treatment of knee osteoarthritis, each has its advantages and shortcomings, and a definitive treatment method is yet to be determined. This pilot study is designed to obtain basic data for a further large-scale trial as well as provide information about the feasibility of thread embedding acupuncture (TEA) with polydioxanone thread in knee osteoarthritis patients.
This study is a clinical trial to evaluate the efficacy and safety of TEA for knee osteoarthritis. Forty participants will be recruited at the hospital and after randomization into 2 groups of 20 (experimental and control); they will be treated for 6 weeks. The experimental group will receive TEA treatment 6 times (1 time/week) in 6 weeks on 14 defined knee areas, and the control group, acupuncture treatments 12 times (2 times/week) in 6 weeks on 9 defined acupuncture points. The visual analogue scale (VAS) will be used for the primary efficacy assessment and Short-form McGill Pain Questionnaire (SF-MPQ), Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) will be used for the secondary efficacy assessment. The follow-ups before clinical trial, 3 weeks after procedure, 6 weeks after procedure, and 4 weeks after the end of procedure will be done to compare the degree of pain with the control group, which received the acupuncture treatment.
The trial based on this study will provide clinical information on the efficacy and safety of TEA treatment on knee osteoarthritis.
KCT0004844.</abstract><cop>United States</cop><pub>Lippincott Williams & Wilkins</pub><pmid>32899030</pmid><doi>10.1097/MD.0000000000021957</doi><orcidid>https://orcid.org/0000-0003-0779-8433</orcidid><oa>free_for_read</oa></addata></record> |
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| language | eng |
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| source | MEDLINE; DOAJ Directory of Open Access Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Wolters Kluwer Open Health; IngentaConnect Free/Open Access Journals; PubMed Central; Alma/SFX Local Collection |
| subjects | Acupuncture Therapy - adverse effects Acupuncture Therapy - methods Humans Osteoarthritis, Knee - therapy Pain Measurement - methods Polydioxanone - therapeutic use Study Protocol Clinical Trial Visual Analog Scale |
| title | Efficacy and safety of thread embedding acupuncture on knee osteoarthritis: A randomized, controlled, pilot clinical trial |
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