Rho-kinase inhibition by Fasudil promotes tumor maturation and apoptosis in small-cell lung cancer

Small-cell lung cancer (SCLC) is a poorly differentiated neuroendocrine neoplasm with inadequate therapeutic options. Fasudil is a Rho-associated protein kinase 1 and 2 (ROCK1/2) inhibitor whose clinical indications remain limited in cardiocerebrovascular diseases. This study aimed to report a possi...

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Veröffentlicht in:	American journal of translational research 2020-01, Vol.12 (8), p.4354-4370
Hauptverfasser:	Huo, Zitian, Su, Yinxia, Dong, Yuting, Zheng, Yiyun, Zhang, Qian, Duan, Yaqi, Wang, Guoping
Format:	Artikel
Sprache:	eng
Schlagworte:	Original
Online-Zugang:	Volltext
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