Premature ovarian insufficiency in the XO female mouse on the C57BL/6J genetic background

Abstract In humans, all but 1% of monosomy 45.X embryos die in utero and those who reach term suffer from congenital abnormalities and infertility termed Turner’s syndrome (TS). By contrast, XO female mice on various genetic backgrounds show much milder physical defects and normal fertility, diminis...

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Veröffentlicht in:	Molecular human reproduction 2020-09, Vol.26 (9), p.678-688
Hauptverfasser:	Vaz, B, El Mansouri, F, Liu, X, Taketo, T
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Female Genetic Background Infertility, Female - genetics Infertility, Female - pathology Male Mice Mice, Inbred C3H Mice, Inbred C57BL Monosomy - genetics Monosomy - pathology Original Pedigree Primary Ovarian Insufficiency - etiology Primary Ovarian Insufficiency - genetics Primary Ovarian Insufficiency - pathology Turner Syndrome - complications Turner Syndrome - genetics X Chromosome - genetics
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