Emergence of behavioural avoidance strategies of malaria vectors in areas of high LLIN coverage in Tanzania
Despite significant reductions in malaria transmission across Africa since 2000, progress is stalling. This has been attributed to the development of insecticide resistance and behavioural adaptations in malaria vectors. Whilst insecticide resistance has been widely investigated, there is poorer und...
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| Veröffentlicht in: | Scientific reports 2020-09, Vol.10 (1), p.14527, Article 14527 |
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| creator | Kreppel, K. S. Viana, M. Main, B. J. Johnson, P. C. D. Govella, N. J. Lee, Y. Maliti, D. Meza, F. C. Lanzaro, G. C. Ferguson, H. M. |
| description | Despite significant reductions in malaria transmission across Africa since 2000, progress is stalling. This has been attributed to the development of insecticide resistance and behavioural adaptations in malaria vectors. Whilst insecticide resistance has been widely investigated, there is poorer understanding of the emergence, dynamics and impact of mosquito behavioural adaptations. We conducted a longitudinal investigation of malaria vector host choice over 3 years and resting behaviour over 4 years following a mass long-lasting insecticidal nets (LLINs) distribution in Tanzania. By pairing observations of mosquito ecology with environmental monitoring, we quantified longitudinal shifts in host-choice and resting behaviour that are consistent with adaptation to evade LLINs. The density of
An. funestus
s.l.
, declined significantly through time. In tandem,
An. arabiensis
and
An. funestus
s.l.
exhibited an increased rate of outdoor relative to indoor resting; with
An. arabiensis
reducing the proportion of blood meals taken from humans in favour of cattle. By accounting for environmental variation, this study detected clear evidence of intra-specific shifts in mosquito behaviour that could be obscured in shorter-term or temporally-coarse surveys. This highlights the importance of mosquito behavioural adaptations to vector control, and the value of longer-term behavioural studies. |
| doi_str_mv | 10.1038/s41598-020-71187-4 |
| format | Article |
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An. funestus
s.l.
, declined significantly through time. In tandem,
An. arabiensis
and
An. funestus
s.l.
exhibited an increased rate of outdoor relative to indoor resting; with
An. arabiensis
reducing the proportion of blood meals taken from humans in favour of cattle. By accounting for environmental variation, this study detected clear evidence of intra-specific shifts in mosquito behaviour that could be obscured in shorter-term or temporally-coarse surveys. This highlights the importance of mosquito behavioural adaptations to vector control, and the value of longer-term behavioural studies.</description><identifier>ISSN: 2045-2322</identifier><identifier>EISSN: 2045-2322</identifier><identifier>DOI: 10.1038/s41598-020-71187-4</identifier><identifier>PMID: 32883976</identifier><language>eng</language><publisher>London: Nature Publishing Group UK</publisher><subject>631/158 ; 631/158/856 ; 692/699 ; 692/699/255 ; 692/699/255/1629 ; Adaptation ; Animals ; Anopheles - parasitology ; Antennae ; Aquatic insects ; Body size ; Cattle ; Coleoptera ; Collembola ; Disease transmission ; Environmental accounting ; Environmental monitoring ; Humanities and Social Sciences ; Humans ; Insecticide Resistance ; Insecticide-Treated Bednets ; Insecticides ; Insecticides - therapeutic use ; Malaria ; Malaria - prevention & control ; Malaria - transmission ; Mandible ; Morphology ; Mosquito Control ; Mosquito Vectors - parasitology ; Mosquitoes ; multidisciplinary ; New species ; Predation ; Prey ; Science ; Science (multidisciplinary) ; Tanzania ; Vector-borne diseases</subject><ispartof>Scientific reports, 2020-09, Vol.10 (1), p.14527, Article 14527</ispartof><rights>The Author(s) 2020</rights><rights>The Author(s) 2020. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c522t-f631c2be2d88c2613c1412ff345c40d739d8694177692c6a3a0979726f81e66c3</citedby><cites>FETCH-LOGICAL-c522t-f631c2be2d88c2613c1412ff345c40d739d8694177692c6a3a0979726f81e66c3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7471940/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7471940/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,315,728,781,785,865,886,27926,27927,41122,42191,51578,53793,53795</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/32883976$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Kreppel, K. S.</creatorcontrib><creatorcontrib>Viana, M.</creatorcontrib><creatorcontrib>Main, B. J.</creatorcontrib><creatorcontrib>Johnson, P. C. D.</creatorcontrib><creatorcontrib>Govella, N. J.</creatorcontrib><creatorcontrib>Lee, Y.</creatorcontrib><creatorcontrib>Maliti, D.</creatorcontrib><creatorcontrib>Meza, F. C.</creatorcontrib><creatorcontrib>Lanzaro, G. C.</creatorcontrib><creatorcontrib>Ferguson, H. M.</creatorcontrib><title>Emergence of behavioural avoidance strategies of malaria vectors in areas of high LLIN coverage in Tanzania</title><title>Scientific reports</title><addtitle>Sci Rep</addtitle><addtitle>Sci Rep</addtitle><description>Despite significant reductions in malaria transmission across Africa since 2000, progress is stalling. This has been attributed to the development of insecticide resistance and behavioural adaptations in malaria vectors. Whilst insecticide resistance has been widely investigated, there is poorer understanding of the emergence, dynamics and impact of mosquito behavioural adaptations. We conducted a longitudinal investigation of malaria vector host choice over 3 years and resting behaviour over 4 years following a mass long-lasting insecticidal nets (LLINs) distribution in Tanzania. By pairing observations of mosquito ecology with environmental monitoring, we quantified longitudinal shifts in host-choice and resting behaviour that are consistent with adaptation to evade LLINs. The density of
An. funestus
s.l.
, declined significantly through time. In tandem,
An. arabiensis
and
An. funestus
s.l.
exhibited an increased rate of outdoor relative to indoor resting; with
An. arabiensis
reducing the proportion of blood meals taken from humans in favour of cattle. By accounting for environmental variation, this study detected clear evidence of intra-specific shifts in mosquito behaviour that could be obscured in shorter-term or temporally-coarse surveys. This highlights the importance of mosquito behavioural adaptations to vector control, and the value of longer-term behavioural studies.</description><subject>631/158</subject><subject>631/158/856</subject><subject>692/699</subject><subject>692/699/255</subject><subject>692/699/255/1629</subject><subject>Adaptation</subject><subject>Animals</subject><subject>Anopheles - parasitology</subject><subject>Antennae</subject><subject>Aquatic insects</subject><subject>Body size</subject><subject>Cattle</subject><subject>Coleoptera</subject><subject>Collembola</subject><subject>Disease transmission</subject><subject>Environmental accounting</subject><subject>Environmental monitoring</subject><subject>Humanities and Social Sciences</subject><subject>Humans</subject><subject>Insecticide Resistance</subject><subject>Insecticide-Treated Bednets</subject><subject>Insecticides</subject><subject>Insecticides - therapeutic use</subject><subject>Malaria</subject><subject>Malaria - prevention & control</subject><subject>Malaria - transmission</subject><subject>Mandible</subject><subject>Morphology</subject><subject>Mosquito Control</subject><subject>Mosquito Vectors - parasitology</subject><subject>Mosquitoes</subject><subject>multidisciplinary</subject><subject>New species</subject><subject>Predation</subject><subject>Prey</subject><subject>Science</subject><subject>Science (multidisciplinary)</subject><subject>Tanzania</subject><subject>Vector-borne diseases</subject><issn>2045-2322</issn><issn>2045-2322</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>C6C</sourceid><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNp1kU9v1DAQxS0EolXpF-CAInEO2GPHfy5IqCpQaQWXcrZmnUnWZTcudjYSfHq83VItB3yxpfebNzN-jL0W_J3g0r4vSnTOthx4a4SwplXP2Dlw1bUgAZ6fvM_YZSl3vJ4OnBLuJTuTYK10Rp-zH9c7yiNNgZo0NGva4BLTPuO2wSXFHg9CmTPONEYqB2aHW8wRm4XCnHJp4tRgJnzQNnHcNKvVzdcmpIUyjnSQb3H6jVPEV-zFgNtCl4_3Bfv-6fr26ku7-vb55urjqg0dwNwOWooAa4Le2gBayCCUgGGQqguK90a63uq6iDHaQdAokTvjDOjBCtI6yAv24eh7v1_vqA801QW2_j7HHeZfPmH0_ypT3PgxLd4oI5zi1eDto0FOP_dUZn9X_2SqM3thrQYHQnWVgiMVciol0_DUQXB_yMgfM_I1I_-QkVe16M3pbE8lfxOpgDwCpUrTSPmk9_9t_wDPFZzt</recordid><startdate>20200903</startdate><enddate>20200903</enddate><creator>Kreppel, K. 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S.</au><au>Viana, M.</au><au>Main, B. J.</au><au>Johnson, P. C. D.</au><au>Govella, N. J.</au><au>Lee, Y.</au><au>Maliti, D.</au><au>Meza, F. C.</au><au>Lanzaro, G. C.</au><au>Ferguson, H. M.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Emergence of behavioural avoidance strategies of malaria vectors in areas of high LLIN coverage in Tanzania</atitle><jtitle>Scientific reports</jtitle><stitle>Sci Rep</stitle><addtitle>Sci Rep</addtitle><date>2020-09-03</date><risdate>2020</risdate><volume>10</volume><issue>1</issue><spage>14527</spage><pages>14527-</pages><artnum>14527</artnum><issn>2045-2322</issn><eissn>2045-2322</eissn><abstract>Despite significant reductions in malaria transmission across Africa since 2000, progress is stalling. This has been attributed to the development of insecticide resistance and behavioural adaptations in malaria vectors. Whilst insecticide resistance has been widely investigated, there is poorer understanding of the emergence, dynamics and impact of mosquito behavioural adaptations. We conducted a longitudinal investigation of malaria vector host choice over 3 years and resting behaviour over 4 years following a mass long-lasting insecticidal nets (LLINs) distribution in Tanzania. By pairing observations of mosquito ecology with environmental monitoring, we quantified longitudinal shifts in host-choice and resting behaviour that are consistent with adaptation to evade LLINs. The density of
An. funestus
s.l.
, declined significantly through time. In tandem,
An. arabiensis
and
An. funestus
s.l.
exhibited an increased rate of outdoor relative to indoor resting; with
An. arabiensis
reducing the proportion of blood meals taken from humans in favour of cattle. By accounting for environmental variation, this study detected clear evidence of intra-specific shifts in mosquito behaviour that could be obscured in shorter-term or temporally-coarse surveys. This highlights the importance of mosquito behavioural adaptations to vector control, and the value of longer-term behavioural studies.</abstract><cop>London</cop><pub>Nature Publishing Group UK</pub><pmid>32883976</pmid><doi>10.1038/s41598-020-71187-4</doi><oa>free_for_read</oa></addata></record> |
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| subjects | 631/158 631/158/856 692/699 692/699/255 692/699/255/1629 Adaptation Animals Anopheles - parasitology Antennae Aquatic insects Body size Cattle Coleoptera Collembola Disease transmission Environmental accounting Environmental monitoring Humanities and Social Sciences Humans Insecticide Resistance Insecticide-Treated Bednets Insecticides Insecticides - therapeutic use Malaria Malaria - prevention & control Malaria - transmission Mandible Morphology Mosquito Control Mosquito Vectors - parasitology Mosquitoes multidisciplinary New species Predation Prey Science Science (multidisciplinary) Tanzania Vector-borne diseases |
| title | Emergence of behavioural avoidance strategies of malaria vectors in areas of high LLIN coverage in Tanzania |
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