The Role of Necroptosis in ROS-Mediated Cancer Therapies and Its Promising Applications

Over the past decades, promising therapies targeting different signaling pathways have emerged. Among these pathways, apoptosis has been well investigated and targeted to design diverse chemotherapies. However, some patients are chemoresistant to these therapies due to compromised apoptotic cell dea...

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Veröffentlicht in:	Cancers 2020-08, Vol.12 (8), p.2185
Hauptverfasser:	Hsu, Sheng-Kai, Chang, Wen-Tsan, Lin, I-Ling, Chen, Yih-Fung, Padalwar, Nitin Balkrushna, Cheng, Kai-Chun, Teng, Yen-Ni, Wang, Chi-Huei, Chiu, Chien-Chih
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Breast cancer Cancer Cancer therapies Care and treatment Caspase Cell death Cell growth Chemotherapy Drug resistance Drugs Enzymes Kinases Leukemia Ligands Molecular modelling Mutation Necroptosis Phosphorylation Physiology Proteins Reactive oxygen species Review Tumor necrosis factor-TNF
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